Trial results for the teleABLE (Activating Behavior for Lasting Engagement) Intervention, aimed at reducing post-stroke sedentary behavior, were posted on ClinicalTrials.gov on 2025-06-29, reporting a median reduction of 32.2 sedentary minutes.
Background
Adults experiencing disability due to stroke often spend more time sedentary compared to those without stroke-related disability. This increased sedentary time can elevate the risk for adverse cardiovascular health outcomes. Currently, there are few interventions specifically designed to reduce sedentary time in individuals post-stroke. The teleABLE Intervention was developed to address this gap, focusing on behavioral activation delivered via telehealth to improve engagement and reduce sedentary behavior within the first 12 months after a stroke.
Trial design
This completed study, designated as Phase NA, enrolled 11 participants to investigate conditions including Stroke, Ischemic Stroke, and Hemorrhagic Stroke. The primary purpose of this research was to test the feasibility and acceptability of the teleABLE (Activating Behavior for Lasting Engagement) Intervention for adults within the first 12 months post-stroke. The intervention utilized videoconferencing for delivery.
Key results
The trial reported several key measurements related to the teleABLE intervention:
- For the Incidence of Treatment-Emergent Adverse Events, two distinct values were reported: 2 adverse events and 0 adverse events.
- Participant Satisfaction was measured with a mean score of 3.7 (Standard Deviation 0.3) on a scale of 1 to 4.
- Change in Participation Restrictions showed a median of 9.5 change in % retained activities.
- Change in Health-Related Quality of Life indicated a median change score of 0.06 on a scale of -1 to 1.
- Change in Sedentary Minutes showed a median reduction of 32.2 sedentary minutes.
What this means
The posted results suggest that the teleABLE intervention is feasible and acceptable for adults within the first 12 months post-stroke, as indicated by the high participant satisfaction score. The reported median reduction in sedentary minutes, alongside changes in participation restrictions and health-related quality of life, provides initial evidence of potential benefits. While the small enrollment of 11 participants means these findings are preliminary, they support the potential of telehealth-delivered behavioral activation to address sedentary behavior in stroke survivors and warrant further investigation in larger studies.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05029284, titled "Behavioral Activation for Post-Stroke Sedentary Behavior Using Telehealth", were posted on 2025-06-29 on clinicaltrials.gov.