Trial results for a study investigating a peer-supported mobile health physical activity intervention for older Latino and Latina adults with Parkinson's Disease were posted on ClinicalTrials.gov on 2025-11-26, indicating high feasibility and acceptability scores among participants.
Background
Parkinson's Disease is a progressive neurodegenerative disorder that primarily affects motor function, leading to symptoms such as tremor, rigidity, bradykinesia, and postural instability. Maintaining physical activity is crucial for managing symptoms and improving quality of life for individuals with Parkinson's Disease. However, adherence to physical activity programs can be challenging, especially within specific cultural contexts and for older adults. Culturally adapted interventions and social support mechanisms, such as peer partnerships and mobile health tools, may help overcome these barriers by providing tailored guidance and encouragement, thereby promoting greater engagement in physical activity.
Trial design
This completed study, identified as Phase NA, enrolled 10 participants diagnosed with Parkinson Disease. The trial aimed to culturally adapt and determine the feasibility of a peer partner training program and a peer-supported mobile health physical activity intervention. The main questions addressed were the feasibility of the peer partner training program and the peer-supported mobile health physical activity intervention, as well as their effects on physical activity, motivation, depression, and apathy.
Key results
The trial results focused on several key measurements related to the intervention's acceptability, appropriateness, and feasibility, as well as its impact on physical activity and quality of life indicators:
- The Acceptability of Intervention Measure (AIM) showed a mean score of 93 with a standard deviation of 8.56.
- The Intervention Appropriateness Measure (IAM) reported a mean score of 89 with a standard deviation of 10.21.
- The Feasibility of Intervention Measure (FIM) had a mean score of 87 with a standard deviation of 11.11.
- Objective Measurement of Physical Activity indicated a mean of 110.77 steps per day with a standard deviation of 1891.27.
- The Behavioral Regulation in Exercise Questionnaire-2 (BREQ-2) showed a mean score of 0.55 with a standard deviation of 1.96.
- The Parkinson's Disease Questionnaire-39 (PDQ-39) reported a mean change of -7.11 with a standard deviation of 8.98, suggesting a potential improvement in quality of life.
- The Geriatric Depression Scale-Short Form showed a mean change of -1.15 with a standard deviation of 2.17, suggesting a potential reduction in depressive symptoms.
What this means
The posted results suggest that the peer partner training program and the peer-supported mobile health physical activity intervention are highly acceptable, appropriate, and feasible for older Latino and Latina adults with Parkinson's Disease. The high mean scores for AIM (93), IAM (89), and FIM (87) indicate that participants found the intervention well-received and practical. The observed mean changes in PDQ-39 (-7.11) and Geriatric Depression Scale-Short Form (-1.15) hint at potential positive impacts on quality of life and mood, although the small sample size of 10 participants means these findings should be interpreted with caution. These feasibility results support the potential for such culturally adapted, peer-supported interventions to promote physical activity and well-being in this specific population, warranting further investigation in larger studies.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT06170866, titled "Peer Partners to Improve Physical Activity in Older Latino and Latina Adults With Parkinson's Disease.", were posted on 2025-11-26 on clinicaltrials.gov.