Trial results for a study comparing Noom Health and Noom Digital Health for weight management in obesity were posted on ClinicalTrials.gov on 2025-08-11, with 600 participants enrolled.
Background
Obesity is a complex chronic disease characterized by excessive body fat, posing significant health risks including type 2 diabetes, cardiovascular disease, and certain cancers. Effective weight management strategies are crucial for improving patient outcomes and quality of life. Digital health interventions, such as mobile applications, have emerged as accessible tools to support individuals in achieving and maintaining weight loss through behavioral changes, dietary tracking, and exercise guidance. This study aimed to compare the efficacy of two distinct Noom app-based programs, Noom Health and Noom Digital Health, for weight loss, weight loss maintenance, and related health metrics.
Trial design
This completed study, designated as Phase NA, enrolled 600 participants to investigate conditions including Weight Loss and Obesity. The trial tested the comparative efficacy of Noom Health versus Noom Digital Health. The study's goals included assessing weight loss, quality of life, psychosocial functioning, and self-reported health status, with an expectation that Noom Health would demonstrate superior post-intervention and long-term success in weight loss maintenance.
Key results
The trial reported several key measurements comparing the two intervention groups:
- Mean Weight at Various Time Points (outcome titled "Change in Weight From Baseline"):
- Noom Health group: Mean weights observed were 210.1 (Standard Deviation 42.1) lbs, 199.4 (Standard Deviation 41.4) lbs, and 197.2 (Standard Deviation 43.1) lbs.
- Noom Digital Health group: Mean weights observed were 211.7 (Standard Deviation 44.7) lbs, 204.6 (Standard Deviation 45.8) lbs, and 201.6 (Standard Deviation 43.6) lbs.
- Mean Caloric Intake Using the Automated Self-Administered Recall System (ASA24) From Baseline to 30 Months:
- Noom Health group: Mean caloric intake was 2186.6 (Standard Deviation 957.3) calories, followed by 1681.7 (Standard Deviation 906.9) calories.
- Noom Digital Health group: Mean caloric intake was 2118.2 (Standard Deviation 908.1) calories, followed by 1578.5 (Standard Deviation 784.8) calories.
- Mean Dietary Behavior Using the Eating Disorder Examination Questionnaire (EDE-Q) From Baseline to 30 Months:
- Noom Health group: Mean score was 2.5 (Standard Deviation 0.9) on a scale.
- Noom Digital Health group: Mean score was 2.6 (Standard Deviation 1.0) on a scale.
What this means
The posted results indicate that participants in the Noom Health group generally achieved slightly lower mean weights at later measurement points compared to those in the Noom Digital Health group. Both interventions demonstrated reductions in mean caloric intake over time. Additionally, the Noom Health group showed a slightly lower mean score on the Eating Disorder Examination Questionnaire (EDE-Q), which may suggest a marginally better dietary behavior profile. These findings suggest potential benefits for the Noom Health program in supporting weight management and related behavioral changes, aligning with the study's objectives to assess comparative efficacy.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT04797169, titled "Noom Health for Weight Management", were posted on 2025-08-11 on clinicaltrials.gov.