Trial results for a pilot study investigating glycemic screening outreach in individuals with Obesity and Overweight were posted on ClinicalTrials.gov on 2026-05-15, involving 102 participants.
Background
Approximately 130 million Americans are estimated to have prediabetes or type 2 diabetes (T2D) but often remain unscreened or unaware of their diagnosis. While national guidelines endorse prediabetes and T2D screening, known as glycemic screening, there is limited research on effective strategies to increase screening rates. This gap highlights the need for interventions that promote screening, especially given quality measures published by organizations like the American Medical Association that track the percentage of adult patients at risk who are screened.
Trial design
This completed pilot study, identified as Phase NA, enrolled 102 participants with conditions including Overweight (BMI > 25) and Obesity. The trial aimed to evaluate interventions promoting glycemic screening. The study explored various outreach strategies, which included combinations of initial and follow-up communications via text messages, patient portals, and letters. A "Usual Care" group served as a comparator.
Key results
The trial results included counts of participants for whom Hemoglobin A1c data was reported across different outreach strategies, as well as an acceptability survey score for intervention participants:
- For the group receiving "Initial Text, Follow-up Text, Letter" outreach, Hemoglobin A1c data was reported for 6 participants.
- For the group receiving "Initial Portal, Follow-up Portal, Letter" outreach, Hemoglobin A1c data was reported for 6 participants.
- For the group receiving "Initial Text, Follow-up Portal, Letter" outreach, Hemoglobin A1c data was reported for 9 participants.
- For the group receiving "Initial Portal, Follow-up Text, Letter" outreach, Hemoglobin A1c data was reported for 7 participants.
- In the "Usual Care" group, Hemoglobin A1c data was reported for 9 participants.
- An "Acceptability Survey" for "Intervention Participants" showed a mean score of 18.5 on a scale, with a dispersion type of "Full Range".
What this means
The posted results provide initial data on the implementation and reception of different glycemic screening outreach strategies for individuals with overweight and obesity. The counts of participants for whom Hemoglobin A1c data was reported across various intervention arms and usual care offer insights into the reach of these pilot strategies. Additionally, the mean acceptability score of 18.5 for intervention participants suggests a level of receptiveness to the outreach efforts. These findings contribute to understanding the feasibility and initial impact of promoting glycemic screening, which is crucial for early detection of prediabetes and type 2 diabetes in at-risk populations.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT06915194, titled "SMART Pilot Trial of Glycemic Screening Outreach", were posted on 2026-05-15 on clinicaltrials.gov.