Trial results for an integrated community health worker-delivered hypertension intervention in individuals with HIV and Hypertension were posted on ClinicalTrials.gov on 2026-02-02. The study reported that 73 out of 100 participants achieved controlled blood pressure at 6-month follow-up.
Background
Individuals living with HIV (PLWH) often face a higher risk of cardiovascular diseases, including hypertension, compared to the general population. Managing hypertension in PLWH is crucial for preventing serious health complications. In regions like northern Tanzania, where healthcare resources may be limited, community-based interventions are vital for improving access to care and promoting chronic disease management. Adapting and assessing multi-component health interventions delivered by community health workers can address the unique challenges faced by PLWH in controlling their blood pressure.
Trial design
This completed study, identified as Phase NA, enrolled 100 participants with both Hypertension and HIV. The trial aimed to adapt and assess the implementation and preliminary effectiveness of an integrated COBRA and CHAMP multi-component community health worker-delivered hypertension intervention. The intervention sought to improve blood pressure control among PLWH in northern Tanzania.
Key results
The trial results focused on the feasibility and preliminary effectiveness of the COACH intervention:
- Feasibility, as measured by the number of total scheduled intervention sessions (CHW counseling sessions, doctor's visits, phone calls) attended, was 589 sessions.
- The number of participants reporting adherence to an anti-hypertensive medication at 6-month follow-up was 91 participants.
- The number of participants with controlled blood pressure at 6-month follow-up was 73 participants.
- Hypertension Knowledge-Level Scale (HK-LS) scores at 6-month follow-up had a mean of 20.4 with a Standard Deviation of 2.0.
What this means
The posted results suggest that the integrated COACH intervention is feasible and shows promising preliminary effectiveness in managing hypertension among people living with HIV. The high number of attended sessions indicates good engagement, while the strong adherence to medication and the significant proportion of participants achieving controlled blood pressure at 6 months highlight the intervention's potential impact. The improvement in hypertension knowledge further supports the comprehensive nature of the community health worker-delivered approach. These findings suggest that such integrated, community-based models could be a valuable strategy for improving cardiovascular health outcomes in PLWH, particularly in resource-constrained settings.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT06503991, titled "Acute Coronary Syndrome KCMC_1", were posted on 2026-02-02 on clinicaltrials.gov.