Trial results for a study investigating HIV-related cancer burden and patient characteristics were posted on ClinicalTrials.gov on 2026-03-25, with 460 participants enrolled.
Background
People living with HIV (PWH) face an increased risk of certain cancers, collectively known as HIV-associated malignancies. These include AIDS-related lymphomas and Kaposi sarcoma, among others. Understanding the prevalence and characteristics of cancers in PWH who seek care is crucial for improving patient outcomes and guiding clinical trial recruitment strategies. This study aimed to describe the burden of HIV-related cancers and patient characteristics within the AIDS Malignancy Consortium (AMC) network.
Trial design
This completed study enrolled 460 participants to investigate conditions including HIV-Associated Malignant Neoplasm, HIV Infections, Cancer, AIDS Related Lymphoma, and AIDS-related Kaposi Sarcoma. The study's objective was to understand the number of people with HIV (PWH) presenting for cancer care at domestic AIDS Malignancy Consortium (AMC) sites and to explore factors influencing their participation in cancer clinical trials.
Key results
The study reported the number of cancers in people with HIV (PWH) who presented for care at domestic AIDS Malignancy Consortium (AMC) sites. Key measurements included:
- For "New, Primary or Recurrent Disease", counts of participants were observed as 43, 87, 30, and 55.
- For "Metastic or Locally Advanced Cancer", counts of participants were observed as 0, 6, 10, and 13.
- For "Prior Cancer", counts of participants were observed as 35, 15, 32, and 55.
What this means
The posted results provide descriptive data on the burden of cancer among people with HIV seeking care at AIDS Malignancy Consortium sites. The varying counts across categories like new, metastatic, and prior cancers highlight the diverse presentations of malignancy in this population. This information is valuable for clinicians and researchers in understanding the scope of HIV-associated cancers and can inform resource allocation and the design of future interventional studies or screening programs aimed at improving cancer care for people with HIV.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05510908, titled "Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC", were posted on 2026-03-25 on clinicaltrials.gov.