Trial results for an observational study focusing on HIV prevention and care in women who inject drugs were posted on ClinicalTrials.gov on 2026-02-20, indicating that 10 participants initiated HIV pre-exposure prophylaxis (PrEP).
Background
Women who inject drugs and engage in exchange sex face heightened risks for HIV, opioid use disorder, and other sexually transmitted infections like Chlamydia, Gonorrhea, and Syphilis. Addressing these interconnected health challenges requires integrated and accessible care models. Pre-exposure prophylaxis (PrEP) is a critical tool for HIV prevention, while Medications for Opioid Use Disorder (MOUD) are essential for treating substance use disorders. Innovative approaches, such as mobile or pop-up clinics, can improve access to these vital services for vulnerable populations who may face barriers to traditional healthcare settings.
Trial design
This completed non-randomized observational clinical trial, designated as Phase NA, enrolled 50 participants. The study focused on women who inject drugs and exchange sex in Seattle, Washington. The trial aimed to assess the impact of a pop-up clinic, housed within a van and operating as an extension of an existing clinic, on the uptake and sustained use of HIV PrEP and MOUD. The conditions of interest for the study cohort included Opioid Use Disorder, HIV Infections, Chlamydia, Gonorrhea, and Syphilis.
Key results
The trial evaluated the uptake of key prevention and treatment services within the study cohort:
- Uptake of Pre-exposure Prophylaxis (PrEP): 10 participants initiated PrEP.
- Uptake of Medications for Opioid Use Disorder (MOUD): 21 participants initiated MOUD.
What this means
The results from this observational trial suggest that a pop-up clinic model can facilitate the uptake of crucial health services among women who inject drugs and exchange sex. The initiation of PrEP by 10 participants and MOUD by 21 participants indicates that this type of accessible, community-based intervention can reach a population often underserved by traditional healthcare. These findings highlight the potential for mobile clinics to improve engagement with HIV prevention strategies and opioid use disorder treatment in high-risk communities.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT06187064, titled "Combination Primary Care and Prevention Services for Women Who Inject Drugs and Exchange Sex in Seattle, Washington", were posted on 2026-02-20 on clinicaltrials.gov.