Trial results for an open-pilot study investigating an online mindfulness-based intervention to reduce minority stress and HIV risk among young adult men who have sex with men (MSM) were posted on ClinicalTrials.gov on 2025-11-19, with 19 participants enrolled.
Background
Young adult gay, bisexual, and queer men, often referred to as men who have sex with men (MSM), face unique challenges, including minority stress, which can impact mental health and increase vulnerability to HIV risk behaviors. Addressing these interconnected issues requires targeted interventions that are accessible and culturally sensitive. Mindfulness-based programs have shown promise in improving mental well-being and coping mechanisms. This study aimed to develop and test an online mindfulness-based program, specifically designed for this population, to assess its feasibility and acceptability as part of a broader intervention development effort.
Trial design
This completed study, designated as Phase NA, enrolled 19 participants to investigate conditions including HIV, Minority Stress, and Mental Health Wellness 1. The trial examined an open-pilot of the Mindfulness-Based Queer Resilience (MBQR) program, an online mindfulness-based intervention. The primary objective of this phase was to seek feedback on the developed program and assess its feasibility and acceptability.
Key results
The trial reported several key measurements related to the feasibility and acceptability of the Online Mindfulness-Based Queer Resilience program:
- Feasibility of Online Mindfulness-Based Queer Resilience as Measured by Recruitment Rates: 19 Participants
- Feasibility of Online Mindfulness-Based Queer Resilience as Measured by Retention Rates: 18 Participants
- Feasibility of Online Mindfulness-Based Queer Resilience as Measured by Retention Rates: 15 Participants
- Feasibility of Online Mindfulness-Based Queer Resilience as Measured by Session Attendance and Home Practice Completion:
- Mean 5.84 Weeks (Standard Deviation 2.14)
- Mean 5.32 Weeks (Standard Deviation 2.29)
- Acceptability of Online Mindfulness-Based Queer Resilience as Measured by the Client Satisfaction Questionnaire: Mean 26.17 (Standard Deviation 5.17) Scores on a scale
- Acceptability of Online Mindfulness-Based Queer Resilience as Measured by a Session Evaluation Form: Mean 16.17 (Standard Deviation 5.25) Scores on a scale
What this means
The posted results indicate that the Online Mindfulness-Based Queer Resilience program demonstrated strong feasibility in terms of recruitment and retention among young adult MSM. The recruitment rate of 19 participants and retention rates of 18 participants and 15 participants suggest that the online format is capable of engaging the target population. Furthermore, the acceptability measures, including mean scores of 26.17 and 16.17 on satisfaction and session evaluation questionnaires respectively, suggest that participants found the program well-received. These findings support the continued development and evaluation of this online intervention for addressing minority stress and HIV risk in this specific demographic.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05540652, titled "Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM", were posted on 2025-11-19 on clinicaltrials.gov.