Trial results for a study on supporting young women's reproductive health, including HIV and contraception, were posted on ClinicalTrials.gov on 2025-06-19. The study found that public feedback mechanisms increased the mean quantity of HIV self-test kits distributed to 239.13, compared to 153.53 in the no-feedback group.
Background
HIV and contraception are critical components of reproductive health, particularly for adolescent girls and young women (AGYW). Ensuring access to HIV self-testing and various contraceptive methods is a public health priority. In many settings, drug shopkeepers serve as accessible points of care for these essential health products. This study explored the impact of customer feedback from AGYW to drug shopkeepers as a strategy to enhance the distribution of contraceptives and HIV self-testing kits, aiming to improve health outcomes for this vulnerable population.
Trial design
This study, designated as Phase NA, was ultimately TERMINATED and enrolled 144 participants. It investigated conditions including Hiv and Contraception. The trial's objective was to operationalize and test the preliminary impact of providing regular customer feedback from adolescent girls and young women to drug shopkeepers on the distribution of contraceptives and HIV self-testing to AGYW over 12 months. The study compared three groups: a 'No Feedback' group, a 'Private Feedback' group, and a 'Public Feedback' group.
Key results
The trial reported several key measurements related to product distribution:
- Quantity of HIV Self-test Kits Distributed (Items sold):
- 'No Feedback' group: Mean of 153.53 (Standard Deviation 203.84)
- 'Private Feedback' group: Mean of 181.13 (Standard Deviation 209.49)
- 'Public Feedback' group: Mean of 239.13 (Standard Deviation 286.70)
- Quantity of Sexual and Reproductive Health Products Sold (Items sold):
- 'No Feedback' group: Mean of 9.68 (Standard Deviation 9.38)
- 'Private Feedback' group: Mean of 9.27 (Standard Deviation 9.06)
- 'Public Feedback' group: Mean of 10.70 (Standard Deviation 9.95)
- Quantity of All Products Sold (items sold):
- 'No Feedback' group: Mean of 11.87 (Standard Deviation 34.19)
- 'Private Feedback' group: Mean of 17.05 (Standard Deviation 36.14)
- 'Public Feedback' group: Mean of 20.11 (Standard Deviation 51.09)
- Quantity of Condoms Sold (items sold):
- 'No Feedback' group: Mean of 3.19 (Standard Deviation 11.16)
- 'Private Feedback' group: Mean of 6.36 (Standard Deviation 21.18)
- 'Public Feedback' group: Mean of 4.63 (Standard Deviation 11.12)
Key analyses using linear regression reported the following mean differences (Final Values) with 95.0% confidence intervals:
- Mean Difference of 0.17 (CI: -1.87 to 2.24)
- Mean Difference of 1.55 (CI: -0.73 to 3.82)
- Mean Difference of 7.58 (CI: -2.92 to 18.0)
- Mean Difference of 16.0 (CI: 0.64 to 31.0)
- Mean Difference of 47.0 (CI: -18.0 to 113.0)
- Mean Difference of 113.0 (CI: 38.0 to 189.0)
The specific outcomes to which these analyses correspond were not detailed in the provided data.
What this means
The results suggest that implementing customer feedback mechanisms, particularly public feedback, can positively influence the distribution of HIV self-test kits and other sexual and reproductive health products by drug shopkeepers. This approach could potentially enhance access to vital health resources for adolescent girls and young women. While the study was terminated, the observed trends in product distribution provide preliminary insights into the effectiveness of prosocial interventions in community health settings.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05525533, titled "Supporting Young Women's Reproductive Health by Harnessing Prosociality Among Drug Shopkeepers", were posted on 2025-06-19 on clinicaltrials.gov.