Trial results for a mobile HIV prevention app for Black women were posted on ClinicalTrials.gov on 2026-03-16, with 56 participants enrolled.
Background
Black women face a significantly higher risk of acquiring HIV compared to their non-Black counterparts. Addressing this disparity requires targeted prevention strategies that are culturally relevant and accessible. Mobile health applications offer a promising avenue for delivering such interventions, particularly in addressing sensitive topics like HIV prevention and reproductive health, and potentially mitigating social stigma associated with these issues.
Trial design
This completed study, designated as Phase NA, enrolled 56 participants to refine and test a mobile HIV Prevention and Reproductive Health app. The study focused on conditions including HIV, Mobile Phone Use, and Social Stigma. Participants were assigned to either the 'In-the-kNOW Mobile App' group or a 'Control Condition'.
Key results
The trial reported several key measurements related to app retention, usability, and impact:
- Retention Rate:
- For the 'In-the-kNOW Mobile App.' group: 20 Participants.
- For the 'Control Condition.' group: 24 Participants.
- App User Retention Rate for the 'In-the-kNOW Mobile App.' group: 70.03 % of first-time app opens retained.
- System Usability Scale (SUS) for the 'In-the-kNOW Mobile App.' group: A mean score of 63.25 (Standard Deviation 13.54) on a scale.
- Impact Scale for the 'In-the-kNOW Mobile App.' group: A mean score of 4.19 (Standard Deviation 0.71) on a scale.
- Perceived Usefulness (PU) Scale for the 'In-the-kNOW Mobile App.' group: A mean score of 3.54 (Standard Deviation 0.63) on a scale.
- Perceived Ease of Use (PEOU) Scale for the 'In-the-kNOW Mobile App.' group: A mean score of 3.69 (Standard Deviation 0.58) on a scale.
- Number of Home Test Kits Ordered by Participants for the 'In-the-kNOW Mobile App.' group: 3 Number of at-home testing kits supplied.
- Number of Participants Indicating Intention to Start PrEP:
- For the 'In-the-kNOW Mobile App.' group: 8 Participants.
- For the 'Control Condition.' group: 12 Participants.
- For the 'In-the-kNOW Mobile App.' group: 11 Participants.
- For the 'Control Condition.' group: 9 Participants.
What this means
The results indicate that the 'In-the-kNOW Mobile App' achieved a user retention rate of 70.03%. The app's usability was assessed with a System Usability Scale mean score of 63.25, suggesting moderate usability. While 3 home test kits were ordered through the app, and participants in both the app group (8 and 11 participants) and control group (12 and 9 participants) indicated an intention to start PrEP, these numbers are descriptive. The study provides initial insights into the feasibility and user experience of a mobile HIV prevention tool for Black women.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05080972, titled 'Mobile HIV Prevention App for Black Women', were posted on 2026-03-16 on clinicaltrials.gov.