Trial results for an intervention aimed at enhancing quality in promoting healthy sexuality and reducing HIV risk were posted on ClinicalTrials.gov on 2026-03-11. The study enrolled 909 participants to assess various outcomes, including abstinence attitudes.
Background
The U.S. invests significantly in community-based organizations to implement research-proven interventions aimed at reducing high rates of unplanned pregnancies, sexually transmitted infections (STIs), and HIV among teenagers. However, there is a recognized gap in the quality of implementation, as communities often struggle to achieve the same outcomes as researchers due to limited resources, the complexity of prevention efforts, and capacity constraints.
Trial design
This completed study, designated as Phase NA, enrolled a total of 909 participants. The trial focused on conditions including Pregnancy in Adolescence and HIV. The study compared two approaches: "Making Proud Choices Alone" and "Making Proud Choices+Getting To Outcomes," both designed to enhance the quality of interventions promoting healthy sexuality.
Key results
The study measured 'Abstinence Attitudes' across two intervention groups:
- For the "Making Proud Choices Alone" group, the mean 'Abstinence Attitudes' score was 4.18 (Standard Deviation 1.02) on a scale.
- For the "Making Proud Choices+Getting To Outcomes" group, the mean 'Abstinence Attitudes' score was 4.17 (Standard Deviation 1.08) on a scale.
- In a separate measurement for the "Making Proud Choices Alone" group, the mean 'Abstinence Attitudes' score was 4.17 (Standard Deviation 1.11) on a scale.
- For the "Making Proud Choices+Getting To Outcomes" group, the mean 'Abstinence Attitudes' score was 4.26 (Standard Deviation 1.05) on a scale.
What this means
The posted results offer insights into the impact of different intervention implementation strategies on abstinence attitudes among participants. The mean scores for 'Abstinence Attitudes' were consistently in a narrow range, with "Making Proud Choices Alone" showing mean scores of 4.18 and 4.17, and "Making Proud Choices+Getting To Outcomes" showing mean scores of 4.17 and 4.26. These measurements, with their respective standard deviations, contribute to understanding how program delivery models may influence participant attitudes related to sexual health and HIV prevention.
Source
The information for this condition update article was sourced from ClinicalTrials.gov, a public registry of clinical studies. The trial results for NCT01818791, titled "Enhancing Quality Interventions Promoting Healthy Sexuality," were posted on 2026-03-11 on clinicaltrials.gov.