Trial results for a study investigating pain in women with Endometriosis, Central Sensitisation, and Dyspareunia were posted on ClinicalTrials.gov on 2026-04-08. The study reported a mean Deep Dyspareunia Score of 3.08 (Standard Deviation 2.32) on a scale in the case group.
Background
Endometriosis is a condition that affects approximately 10% of reproductive-aged females. It can significantly impact sexual quality of life, often causing pelvic pain during deep penetration during intercourse, as well as other sexual and non-sexual pains. This study aimed to explore the relationship between increased sexual pain and central sensitization in women with endometriosis, seeking to determine if an association exists between the severity of sexual pain and central sensitization.
Trial design
This completed study enrolled 56 subjects. The conditions investigated included Endometriosis, Central Sensitisation, and Dyspareunia. The study's purpose was to determine if there is an association between the severity of sexual pain and central sensitization in women with endometriosis. No specific interventions or comparator arms were listed, as the study focused on observational measurements within a case group.
Key results
The study reported the following key measurements for the Case group:
- Deep Dyspareunia Score: The mean score was 3.08 (Standard Deviation 2.32) on a scale.
- Superficial Dyspareunia Score: The mean score was 2.34 (Standard Deviation 2.34) on a scale.
- Chronic Pelvic Pain Score: The mean score was 2.68 (Standard Deviation 1.76) on a scale.
What this means
These results provide quantitative measures of the severity of deep dyspareunia, superficial dyspareunia, and chronic pelvic pain in the studied population of women with endometriosis. The reported mean scores offer insights into the pain experience in this group, which is relevant to the study's objective of exploring the association between sexual pain severity and central sensitization. As an observational study, it characterizes the pain profiles but does not test the efficacy of an intervention.
Source
The information for these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT03216330, titled "Dyspareunia and Central Sensitization", were posted on 2026-04-08 on clinicaltrials.gov.