Trial results for Project ASTHMA, a school-based intervention for children with asthma, were posted on ClinicalTrials.gov on 2026-02-09, showing the intervention group reduced daytime asthma symptoms by 3.4 days per week.
Background
Asthma is a chronic respiratory condition affecting millions of children, often leading to symptoms like wheezing, coughing, and shortness of breath. Effective management is crucial to improve quality of life, prevent exacerbations, and reduce school absenteeism. Project ASTHMA aimed to address these challenges by implementing guideline-based chronic asthma care within school-based health centers, including supervised administration of daily preventive medications. This approach sought to improve asthma symptoms and lung function, reduce emergency visits, and decrease missed school days among children from communities facing health disparities.
Trial design
This completed study, designated as Phase NA, enrolled 29 participants with Asthma. The intervention involved a school-based health center program providing guideline-based chronic asthma care and supervised administration of daily preventive asthma medications. Participants were compared against a 'Usual Care' group.
Key results
The trial reported the following key measurements at 7-month follow-up:
- Change in Number of Days Per Week, in the Previous 4 Weeks, of Daytime Asthma Symptoms From Baseline to 7-month Follow-up:
- The Intervention group showed a mean change of -3.4 days per week.
- The Usual Care group showed a mean change of -2.8 days per week.
- Change in ACT Score From Baseline to 7-month Follow-up:
- The Intervention group showed a mean change of 6.4 score on a scale.
- The Usual Care group showed a mean change of 8.3 score on a scale.
- Change in FEV1/FVC Ratio From Baseline to 7-month Follow-up:
- The Intervention group showed a mean change of 0 ratio.
- The Usual Care group showed a mean change of -0.05 ratio.
What this means
The results suggest that the school-based intervention, Project ASTHMA, led to a greater reduction in the number of days per week with daytime asthma symptoms compared to usual care, with the intervention group experiencing a mean reduction of 3.4 days per week versus 2.8 days per week in the usual care group. Regarding lung function, the FEV1/FVC ratio remained stable in the intervention group (0 change), while it showed a slight decrease in the usual care group (-0.05 change). However, the change in ACT (Asthma Control Test) score, a measure of asthma control, was numerically higher in the usual care group (8.3) compared to the intervention group (6.4). These findings indicate mixed outcomes, with the intervention showing benefits in symptom reduction and lung function stability, but usual care showing a greater improvement in ACT scores.
Source
The information for this condition update was sourced from ClinicalTrials.gov, a public database of clinical studies. The trial results for study NCT03032744, titled "Aligning With Schools To Help Manage Asthma (Project ASTHMA)", were posted on 2026-02-09 on clinicaltrials.gov.