Trial results for a study investigating digital interventions in Alzheimer's Disease were posted on ClinicalTrials.gov on 2026-01-22, with 48 participants enrolled.
Background
Alzheimer's Disease is a progressive neurodegenerative disorder that impacts memory, thinking, and behavior, often leading to dementia. A common and distressing symptom for individuals with dementia is anomia, or difficulty recalling names, particularly those of familiar people. This can lead to feelings of upset and embarrassment for patients and their caregivers. While memory loss is a hallmark of the disease, evidence suggests that targeted practice can help individuals re-learn and retain names. The 'Gotcha!' intervention was developed to provide a structured, engaging way for people with dementia to practice recalling important names.
Trial design
This completed study, designated as Phase NA, enrolled 48 participants to investigate conditions including Dementia, Alzheimer Disease, and Anomia. The trial explored a digital intervention named 'Gotcha!', designed as a therapy to help participants practice and remember the names of important people. The primary outcomes were not specified in the provided data.
Key results
The trial reported several key measurements related to the 'Gotcha! Outcome Measure':
- For 'Familar Faces (Trained Items)', a mean of 20 percentage was observed.
- For 'Famous Faces (Unrained Items)', a mean of 18 percentage was observed.
- Another measurement for 'Familar Faces (Trained Items)' showed a mean of 59 percentage.
- Another measurement for 'Famous Faces (Unrained Items)' showed a mean of 17 percentage.
What this means
The posted results provide specific mean percentages for the 'Gotcha! Outcome Measure' across both familiar and famous faces, distinguishing between trained and untrained items. While these figures offer insights into the performance on the digital intervention, the data does not include comparative analyses, baseline measures, or statistical significance, which would be necessary to fully interpret the clinical implications or the direction of effect. The study aimed to provide practice for re-learning names, and these percentages reflect outcomes from that intervention.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT04570215, titled 'Digital Interventions in Neuro-Rehabilitation: Gotcha!', were posted on 2026-01-22 on clinicaltrials.gov.