A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction Cancer

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT07631000
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Cadonilimab — DRUG
    Perioperative cadonilimab plus neoadjuvant chemotherapy

Study Details

The purpose of this study is to find out whether adding cadonilimab to the usual chemotherapy approach is an effective and safe treatment for participants with locally advanced/resectable gastric cancer or gastroesophageal junction (GEJ) cancer

Key Dates

Start date
May 27, 2026
Status verified
Jun 2026
Primary completion
May 27, 2029
Completion
May 27, 2029

Study Design

Enrollment
37 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Participants with HER2-negative gastric or GEJ adenocarcinoma
    Participants will have locally advanced, resectable, HER2-negative gastric or GEJ adenocarcinoma

Primary Outcome Measure

Event-free survival (EFS) rata [ Time Frame: 18 months ]

Central Contacts

Locations (7)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)Basking RidgeNew Jersey07920
Yelena Janjigian, MD
646-888-4286
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)MiddletownNew Jersey07748
Yelena Janjigian, MD
646-888-4286
Memorial Sloan Kettering Bergen (Limited Protocol Activities)MontvaleNew Jersey07645
Yelena Janjigian, MD
646-888-4286
Memorial Sloan Kettering Suffolk-Commack (Limited protocol activity)CommackNew York11725
Yelena Janjigian, MD
646-888-4286
Memorial Sloan Kettering Westchester (Limited Protocol Activities)HarrisonNew York10604
Yelena Janjigian, MD
646-888-4286
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New YorkNew York10065
Yelena Y Janjigian, MD
646-888-4286
Memorial Sloan Kettering Nassau (Limited Protocol Activities)UniondaleNew York11553
Yelena Janjigian, MD
646-888-4286

Find similar trials in Basking Ridge, NJ

By condition
Gastric cancer
By specialty
OncologyGI oncology
By research site
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)· Basking Ridge, NJMemorial Sloan Kettering Monmouth (Limited Protocol Activities)· Middletown, NJMemorial Sloan Kettering Bergen (Limited Protocol Activities)· Montvale, NJMemorial Sloan Kettering Suffolk-Commack (Limited protocol activity)· Commack, NYMemorial Sloan Kettering Westchester (Limited Protocol Activities)· Harrison, NYMemorial Sloan Kettering Cancer Center (All Protocol Activities)· New York, NY

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