Dorsal Root Ganglion Stimulation After Lower Motor Neuron Damage

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Peter J. Grahn, Ph.D.
Study ID
NCT07619300
Status
Not Yet Recruiting

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Conditions

  • Lower Motor Neuron Disease
  • Spinal Cord Injuries

Eligibility Criteria

Sex
ALL
Age
18 Years - 70 Years
Healthy Volunteers
Not accepted

Interventions

  • Abbot Dorsal Root Ganglion Neurostimulator — DEVICE
    After temporary implantation of leads into the dorsal root ganglia of lower spine, the patient will undergo 2-3 hour sessions over 10 days. Each session will consist of rehabilitation exercises will receiving electrical spinal stimulation.

Study Details

The purpose of this study is to study sensorimotor circuit activity generated in response to temporarily implanted dorsal root ganglion stimulation by recording from muscles of the lower extremities as well as functional outcomes achieved over a 10-day rehabilitation program in an individual with lower motor neuron injury.

Key Dates

Start date
Jul 31, 2026
Status verified
Jun 2026
Primary completion
Jun 30, 2027
Completion
Sep 30, 2027

Study Design

Enrollment
1 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Dorsal Root Ganglion Stimulation
    One adult patient with spinal cord injury below T10 will be treated with dorsal root ganglion stimulation.

Primary Outcome Measure

Change America Spinal Injury Association (ASIA) Impairment Scale categorization [ Time Frame: Baseline, 14 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo ClinicRochesterMinnesota55905
Peter J. Grahn, Ph.D.
[email protected]
507-316-5556

Find similar trials in Rochester, MN

By research site
Mayo Clinic· Rochester, MN

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