Exosome-based Omic Signatures of Disease Activity in Cardiac Sarcoidosis (EXODACS)

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT07604220
Status
Not Yet Recruiting

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Conditions

  • Cardiac Sarcoidosis
  • Sarcoidosis With Myocarditis
  • Sarcoidosis of the Heart
  • Sarcoidosis, Cardiac

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Exosome Analysis — OTHER
    Blood Samples will undergo exosome profiling using mass spectrometry and/or other discovery-based approaches

Study Details

The purpose of this study is to develop a prospective cohort of patients with and without cardiac sarcoidosis as well as active and inactive disease to develop a prospective biobank from which exosome analysis of peripheral blood will derive unique biomarkers of disease activity in cardiac sarcoidosis.

Key Dates

Start date
Jul 31, 2026
Status verified
May 2026
Primary completion
Jul 31, 2028
Completion
Jul 31, 2028

Study Design

Enrollment
115 participants (estimated)

Arms

  • Arm: Cardiac Sarcoidosis Patients
    Patients with a clinical suspicion or a previously confirmed diagnosis of cardiac sarcoidosis.

Primary Outcome Measure

Number of successful biomarker validations [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905
Anna Pick
[email protected]
507-255-0630
Andrew Rosenbaum, MD
[email protected]
(507) 284-0783
Andrew Rosenbaum, MD (PRINCIPAL_INVESTIGATOR)

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