A Phase IIb/III Clinical Study to Evaluate the Efficacy and Safety of APC101 in Patients With Postherpetic Neuralgia.

Part of paid clinical trials in Florida City, Florida.

Sponsor
Andros Pharmaceuticals Co., Ltd.
Study ID
NCT07599800
Phase
PHASE2/PHASE3
Status
Not Yet Recruiting

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Conditions

  • PHN - Post-Herpetic Neuritis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • APC101 — DRUG
    Lidocaine spray 5% solution
  • Control — OTHER
    A vehicle spray solution

Study Details

APC101 is developed to provide continuous lidocaine administration over 24 hours and is safe when administered to intact skin. Dispensing from a metered-dose spray pump, APC101 provides once or twice daily flexible dosing options that deliver medication without physically touching the afflicted allodynic skin site, resulting in very light, minimal contact with the painful, hypersensitive skin affected by PHN.

Key Dates

Start date
Aug 1, 2026
Status verified
May 2026
Primary completion
Dec 31, 2028
Completion
Dec 31, 2029

Study Design

Enrollment
333 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: APC101
    Lidocaine spray 5% solution
  • Placebo Comparator: Control
    Vehicle spray solution

Primary Outcome Measure

NRS-11 [ Time Frame: From baseline (Week -1; within 7 days ending on the date of randomization) to the evaluation conducted within 7 days ending on the date of the end of treatment (EOT). ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Suncoast Clinical ResearchFlorida CityFlorida34652-

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