rTMS Induced Reduction in M1 Excitability

Part of paid clinical trials in Indianapolis, Indiana.

Sponsor
Indiana University
Study ID
NCT07588113
Status
Recruiting
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Conditions

  • Cortical Excitability
  • Motor Skills
  • Primary Motor Cortex

Eligibility Criteria

Sex
ALL
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Interventions

  • rTMS — DEVICE
    in the arm/group descriptions

Study Details

When learning a new skill, much of the improvement comes from small alterations the brain makes with each repetition during practice, but this isn't the only time that improvements are made during the learning process. Individuals also get better at the motor skills during the time between practices, through a process called "consolidation." It is known that an area of the brain called the primary motor cortex is involved in learning during active practice, but the investigators want to study if the primary motor cortex is important for consolidation. The investigators will examine how lowering the activity in this brain region affects your ability to consolidate learning to play a song on the videogame Guitar Hero.

Key Dates

Start date
Apr 23, 2026
Status verified
May 2026
Primary completion
Apr 23, 2027
Completion
Apr 23, 2027

Study Design

Enrollment
32 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: rTMS stimulation group
    this group will receive 15 minutes of repetitive transcranial magnetic stimulation of the motor cortex while seated quietly
  • Placebo Comparator: SHAM stimulation group
    This group will have the same stimulating wand placed over the head, but at a distance far enough away as to not activate the cortical neurons.

Primary Outcome Measure

Gaming outcome [ Time Frame: 3 sessions, sessions 1 & 2 on the first day and session 3 on the follow-up day (next day) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
National Institute for Fitness and SportIndianapolisIndiana46202
Zachary Riley
[email protected]

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By research site
National Institute for Fitness and Sport· Indianapolis, IN

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