Lesion-tailored, Fundus-controlled Perimetry in Geographic Atrophy (GA).

Part of paid clinical trials in Salt Lake City, Utah.

Sponsor
University of Utah
Study ID
NCT07582042
Status
Not Yet Recruiting

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Conditions

  • Geographic Atrophy From Age-related Macular Degeneration

Eligibility Criteria

Sex
ALL
Age
65 Years - 90 Years
Healthy Volunteers
Not accepted

Study Details

The goal of this observational study is to evaluate changes in retinal sensitivity over time in patients with geographic atrophy due to age related macular degeneration who are receiving pegcetacoplan as part of routine clinical care. The study aims to determine whether lesion tailored fundus-controlled perimetry can reliably measure functional changes near areas of atrophy and whether this testing can be implemented in everyday clinic care over 24 months. Participants will undergo repeated vision testing, standard eye imaging, and visual function questionnaires while continuing their prescribed treatment.

Key Dates

Start date
May 15, 2026
Status verified
May 2026
Primary completion
May 1, 2029
Completion
Aug 1, 2029

Study Design

Enrollment
50 participants (estimated)

Primary Outcome Measure

Slope of mesopic retinal sensitivity decline (dB/year) at predefined distances from the Geographic Atrophy (GA) border. [ Time Frame: Duration per participant: 24 months (36-month total project timeline including start-up, ~6-month recruitment, and ~3-month close-out/analysis). ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Utah, Department of Ophthalmology, John A. Moran Eye CenterSalt Lake CityUtah84132-

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University of Utah, Department of Ophthalmology, John A. Moran Eye Center· Salt Lake City, UT

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