Cardiometabolic Disease and Substrate Metabolism

Part of paid clinical trials in Knoxville, Tennessee.

Sponsor
University of Tennessee Graduate School of Medicine
Study ID
NCT07565727
Status
Recruiting
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Conditions

  • Cardiometabolic Diseases
  • Gestational Complications
  • Gestational Diabetes
  • Gestational Diabetes Mellitus (GDM)
  • Gestational Diabetes Mellitus in Pregnancy
  • Insulin Resistance
  • Placental Dysfunction
  • Preeclampsia
  • Preeclampsia (PE)
  • Preeclampsia (PE) Risk
  • Pregnancy
  • Pregnancy Complications

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 45 Years
Healthy Volunteers
Not accepted

Study Details

This study's primary purpose is to determine the potential relationship between cardiometabolic disease, specifically insulin resistance (HOMA-IR), and maternal lipid oxidation.

Key Dates

Start date
Dec 10, 2025
Status verified
Jan 2026
Primary completion
Aug 31, 2026
Completion
Aug 31, 2027

Study Design

Enrollment
50 participants (estimated)

Arms

  • Arm: Pregnant individuals at risk for cardiometabolic disease

Primary Outcome Measure

Early Pregnancy Fasting Insulin (mIU/mL) [ Time Frame: Fasting, at the beginning of a single study visit between 12-18 weeks gestational age ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Tennessee Graduate School of MedicineKnoxvilleTennessee37920
Jill M Maples, PhD
[email protected]
865-305-9367
Hana O El-Messidi, BS
[email protected]
865-305-5592
Jacklyn Locklear, MD (PRINCIPAL_INVESTIGATOR)

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University of Tennessee Graduate School of Medicine· Knoxville, TN

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