A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health

Part of paid clinical trials in Washington D.C., District of Columbia.

Sponsor
International AIDS Vaccine Initiative
Study ID
NCT07565090
Phase
PHASE1
Status
Not Yet Recruiting

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Conditions

  • Sudan Virus Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - 50 Years
Healthy Volunteers
Accepted

Interventions

  • rVSVΔG-SUDV-GP — BIOLOGICAL
    rVSVΔG-SUDV-GP
  • Placebo — OTHER
    Placebo

Study Details

A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health.

Key Dates

Start date
May 31, 2026
Status verified
May 2026
Primary completion
Apr 30, 2027
Completion
Apr 30, 2027

Study Design

Enrollment
112 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Experimental: rVSVΔG-SUDV-GP
    rVSVΔG-SUDV-GP
  • Placebo Comparator: Placebo
    Placebo/Diluent

Primary Outcome Measure

Safety and tolerability of rVSVΔG-SUDV-GP vaccination: solicited reactogenicity [ Time Frame: 14 Days ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
George Washington UniversityWashington D.C.District of Columbia20037
Christina Gibbs Tewary
202-994-2909
Aimee Desrosiers
David Diemert, MD (PRINCIPAL_INVESTIGATOR)
Johnson County Clin-TrialsLenexaKansas66219
Thomas Kreamer, MD
913-825-4400
Brigham and Women's HospitalBostonMassachusetts02115
Natalie Izaguirre
617-732-6801
Lindsey Baden, MD (PRINCIPAL_INVESTIGATOR)

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