Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS

Part of paid clinical trials in Los Angeles, California.

Sponsor
Jessica K. Stewart, MD
Study ID
NCT07559630
Status
Recruiting
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Conditions

  • HAE
  • Hemorrhoidal Bleeding
  • Hemorrhoids, Internal
  • RBL

Eligibility Criteria

Sex
ALL
Age
18 Years - 89 Years
Healthy Volunteers
Not accepted

Interventions

  • Hemorrhoidal Artery Embolization — DEVICE
    Involves using a catheter inserted into an artery to put tiny particles or coils into the blood vessel that feeds the hemorrhoid to block the blood flow and shrink it.
  • Rubber Band Ligation — PROCEDURE
    Involves using a band to cut off blood flow to the hemorrhoid and shrink it.

Study Details

The purpose of this clinical trial is to compare two standard of care non-surgical treatments for hemorrhoidal bleeding: hemorrhoidal artery embolization (HAE) versus rubber band ligation (RBL). Directly comparing these two methods may help to clarify which treatment is better for controlling hemorrhoidal bleeding, reducing symptoms, and improving patients' quality of life. HAE is a standard minimally invasive procedure to put tiny particles or coils into the blood vessel that feeds a hemorrhoid to block the blood flow (embolization). This involves using a catheter inserted into an artery, using twilight (conscious) sedation. RBL is a standard procedure that involves using small rubber bands around the base of the hemorrhoids to cut off blood flow, causing it to shrink or shrivel.

Key Dates

Start date
May 29, 2026
Status verified
May 2026
Primary completion
Nov 30, 2030
Completion
Nov 30, 2031

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Active Comparator: Hemorrhoidal Artery Embolization
    Involves using a catheter inserted into an artery to put tiny particles or coils into the blood vessel that feeds the hemorrhoid to block the blood flow and shrink it.
  • Active Comparator: Rubber Band Ligation
    Involves using a band to cut off blood flow to the hemorrhoid and shrink it.

Primary Outcome Measure

Number of procedures to control bleeding [ Time Frame: 6 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Ronald Reagan UCLA Medical CenterLos AngelesCalifornia90095
Jessica Stewart, MD
[email protected]
310-267-8769

Find similar trials in Los Angeles, CA

By research site
Ronald Reagan UCLA Medical Center· Los Angeles, CA

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