A Study of Ivonescimab in People With Leiomyosarcoma

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT07516925
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

  • Leiomyosarcoma

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Ivonescimab — DRUG
    Ivonescimab is administered IV Q3W on Day 1 of each cycle

Study Details

The purpose of this study is to find out if Ivonescimab is an effective and safe treatment that causes few or mild side effects for people with advanced/unresectable leiomyosarcoma.

Key Dates

Start date
Apr 1, 2026
Status verified
Jun 2026
Primary completion
Apr 30, 2029
Completion
Apr 30, 2029

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Ivonescimab
    Ivonescimab is administered IV Q3W on Day 1 of each cycle. The total duration of ivonescimab treatment is up to 24 months.

Primary Outcome Measure

Response [ Time Frame: up to two years ]

Central Contacts

  • Sandra D'Angelo, MD
    646-888-4159
    zzPDL_MED_Sarcoma_Clinical_Trials <[email protected]>
  • Sujana Movva, MD
    646-888-6787

Locations (7)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)Basking RidgeNew Jersey07920
Sandra D'Angelo, MD
[email protected]
646-888-4159
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)MiddletownNew Jersey07748
Sandra D'Angelo, MD
[email protected]
646-888-4159
Memorial Sloan Kettering Bergen (Limited Protocol Activities)MontvaleNew Jersey07645
Sandra D'Angelo, MD
[email protected]
646-888-4159
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)CommackNew York11725
Sandra D'Angelo, MD
[email protected]
646-888-4159
Memorial Sloan Kettering Westchester (Limited Protocol Activities)HarrisonNew York10604
Sandra D'Angelo, MD
[email protected]
646-888-4159
Memorial Sloan Kettering Cancer CenterNew YorkNew York10065
Sandra D'Angelo, MD
[email protected]
646-888-4159
Sujana Movva, MD
646-888-6787
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Rockville CentreNew York11553
Sandra D'Angelo, MD
[email protected]
646-888-4159

Find similar trials in Basking Ridge, NJ

By research site
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)· Basking Ridge, NJMemorial Sloan Kettering Monmouth (Limited Protocol Activities)· Middletown, NJMemorial Sloan Kettering Bergen (Limited Protocol Activities)· Montvale, NJMemorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)· Commack, NYMemorial Sloan Kettering Westchester (Limited Protocol Activities)· Harrison, NYMemorial Sloan Kettering Cancer Center· New York, NY

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