The Primary Purpose of This Study is to Determine if Biotin, Vitamin B7 is an Effective Way to Label Platelets in Survival and Recovery Studies.

Part of paid clinical trials in Seattle, Washington.

Sponsor
Bloodworks
Study ID
NCT07513532
Phase
PHASE1
Status
Recruiting
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Conditions

  • Healthy Volunteers

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Biotin labeled platelets — BIOLOGICAL
    Biotin labeled platelets stored at room temperature for 3 days.

Study Details

This is a platelet transfusion study. The primary purpose of this study is to determine if Biotin, vitamin B7 is an effective way to label platelets in survival and recovery studies. This study involves using a radioactive material as well as Biotin added to platelets to track platelets in the blood. The platelets will be collected using an apheresis procedure, labeled with biotin, and stored for 3 days. After the storage period, a radioactive material will be added to a small amount of the stored biotin-treated platelets. The radiolabeled platelets will be given back to donor and follow-up blood draws will be done to see how many of the platelets are circulating.

Key Dates

Start date
Apr 6, 2026
Status verified
Mar 2026
Primary completion
Aug 31, 2026
Completion
Nov 30, 2026

Study Design

Enrollment
12 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Biotin labeled platelets
    Donor platelets labeled with biotin,

Primary Outcome Measure

Primary Endpoint Recovery and Survival [ Time Frame: 12 days post infusion ]

Locations (1)

FacilityCityStateZIPSite coordinators
Bloodworks Northwest Research InstituteSeattleWashington98102
Patricia L Klotz, BSN
[email protected]
206-568-2238
Moritz Stolla, MD (PRINCIPAL_INVESTIGATOR)

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By research site
Bloodworks Northwest Research Institute· Seattle, WA

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