A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
Ollin Biosciences, Inc.
Study ID
NCT07484074
Phase
PHASE1
Status
Completed

Conditions

  • Diabetic Macular Edema (DME)
  • Neovascular (Wet) Age-Related Macular Degeneration

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Faricimab — DRUG
    Intravitreal Injection
  • OLN324 — DRUG
    Intravitreal Injection

Study Details

A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324

Key Dates

Start date
Feb 12, 2025
Status verified
Mar 2026
Primary completion
Oct 10, 2025
Completion
Dec 9, 2025

Study Design

Enrollment
164 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: faricimab 6mg
  • Experimental: OLN324 2mg
  • Experimental: OLN324 4mg

Primary Outcome Measure

Adverse Events [ Time Frame: Week 12 and Week 20 ]

Locations (29)

FacilityCityStateZIPSite coordinators
Phoenix, AZPhoenixArizona85016-
Glendale, CAGlendaleCalifornia91204-
Pasadena, CAPasadenaCalifornia91107-
Sacramento, CASacramentoCalifornia95825-
Walnut Creek, CAWalnut CreekCalifornia94598-
Waterford, CTWaterfordConnecticut06385-
Fort Myers, FLFort MyersFlorida33912-
Saint Petersburg, FLSt. PetersburgFlorida33711-
Winter Haven, FLWinter HavenFlorida33880-
Oak Forest, ILOak ForestIllinois60452-
Hagerstown, MDHagerstownMaryland21740-
Grand Rapids, MIGrand RapidsMichigan49546-
Reno, NVRenoNevada89502-
Wake Forest, NCWake ForestNorth Carolina27587-
Tulsa, OKTulsaOklahoma74114-
Springfield, ORSpringfieldOregon97477-
Germantown, TNGermantownTennessee38138-
Abilene, TXAbileneTexas79606-
Arlington, TXArlingtonTexas76012-
Austin, TXAustinTexas78705-
Bellaire, TXBellaireTexas77401-
Dallas, TXDallasTexas75231-
Katy, TXKatyTexas77494-
Plano, TXPlanoTexas75075-
Round Rock, TXRound RockTexas78681-
San Antonio, TXSan AntonioTexas78240-
San Marcos, TXSan MarcosTexas78666-
Schertz, TXSchertzTexas78154-
The Woodlands, TXThe WoodlandsTexas77384-

Find similar trials in Phoenix, AZ

By research site
Phoenix, AZ· Phoenix, AZGlendale, CA· Glendale, CAPasadena, CA· Pasadena, CASacramento, CA· Sacramento, CAWalnut Creek, CA· Walnut Creek, CAWaterford, CT· Waterford, CT

Related Studies