Rimegepant Combined With AG Chemotherapy As First-Line Treatment For Metastatic Pancreatic Ductal Adenocarcinoma
- Sponsor
- Xiuchao Wang
- Study ID
- NCT07475234
- Phase
- PHASE1/PHASE2
- Status
- Not Yet Recruiting
Notify me when recruiting opens
Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.
Add your contact details and location so we can keep your interest tied to this study.
Conditions
- Metastatic Pancreatic Ductal Adenocarcinoma
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Rimegepant plus Nab-Paclitaxel and Gemcitabine — DRUGRimegepant 75 mg every other day. Nab-paclitaxel 125 mg/m² and Gemcitabine 1000 mg/m² intravenously on Days 1 and 8 of a 21-day cycle.
Study Details
This study aims to evaluate the efficacy and safety of Rimegepant combined with AG chemotherapy as first-line treatment for metastatic pancreatic cancer.
Key Dates
- Start date
- Mar 31, 2026
- Status verified
- Mar 2026
- Primary completion
- Dec 31, 2028
- Completion
- Dec 31, 2028
Study Design
- Enrollment
- 30 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Single-ArmPatients receive Rimegepant combined with AG chemotherapy as first-line treatment for metastatic pancreatic cancer, with assessment of efficacy and safety outcomes.
Primary Outcome Measure
Progression-Free Survival [ Time Frame: From randomization to disease progression or death, with follow-up for up to 2 years after treatment initiation. ]
Central Contacts
- Xiuchao W Chief Physician+86 13752038814
Related Studies
- Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal CancerPHASE1 · Recruiting · M.D. Anderson Cancer Center · Houston, Texas
- Targeted Pathway Inhibition in Patients With Pancreatic CancerEARLY_PHASE1 · Recruiting · OHSU Knight Cancer Institute · Portland, Oregon
- SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem CellsPHASE1 · Recruiting · General Oncology, Inc. · Boston, Massachusetts
- Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid TumorsPHASE1/PHASE2 · Recruiting · Revolution Medicines, Inc. · Chandler, Arizona