A Study to Evaluate the Impact of a Magnolia Officinalis Dietary Supplement on Immune Biomarkers in Subjects With Psoriasis
Part of paid clinical trials in Englewood, New Jersey.
- Sponsor
- Sirt3 LLC
- Study ID
- NCT07471048
- Status
- Recruiting
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Oral supplement containing 200mg Magnolia officinalis bark extract — DIETARY_SUPPLEMENTViv is a consumer grade oral supplement containing 200mg Magnolia officinalis bark extract encapsulated in a hypromellose capsule.
- Placebo — DIETARY_SUPPLEMENTOral hypromellose capsule with all inactive ingredients but lacking the Magnolia officinalis bark extract
Study Details
The goal of this clinical trial is to evaluate whether Viv, a consumer-grade dietary supplement derived from the Magnolia officinalis plant, has an effect on biomarkers of immune activity in adults with psoriasis. To address this question, this trial will compare Viv to a placebo (a look-alike substance that contains no drug). Participants will: * Take Viv or a placebo every day for 3 months. * Complete electronic questionnaires about their quality of life and psoriasis symptoms at the beginning of the study and again at 1 months and 3 months. * Be provided with at home blood collection kits, which they will use to collect blood at the beginning of the study and again at 1 months and 3 months. Researchers will analyze these blood samples to measure the levels of specific inflammatory proteins and evaluate how they change over the course of the study in the participants taking Viv compared to those taking placebo.
Key Dates
- Start date
- Mar 1, 2026
- Status verified
- Mar 2026
- Primary completion
- Sep 1, 2028
- Completion
- Sep 1, 2029
Study Design
- Enrollment
- 100 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- BASIC_SCIENCE
Arms
- Experimental: VivMagnolia officinalis study arm
- Placebo Comparator: PlaceboPlacebo control study arm
Primary Outcome Measure
Relative change in plasma Beta defensin 2 from baseline [ Time Frame: From baseline to the end of study product/placebo use at 12 weeks ]
Central Contacts
- Adeeb Rahman, PhD2013596845
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Decentralized Study Coordinating Center | Englewood | New Jersey | 07631 | Viv Clinical Trial Operations |
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