A Study to Evaluate the Impact of a Magnolia Officinalis Dietary Supplement on Immune Biomarkers in Subjects With Psoriasis

Part of paid clinical trials in Englewood, New Jersey.

Sponsor
Sirt3 LLC
Study ID
NCT07471048
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Oral supplement containing 200mg Magnolia officinalis bark extract — DIETARY_SUPPLEMENT
    Viv is a consumer grade oral supplement containing 200mg Magnolia officinalis bark extract encapsulated in a hypromellose capsule.
  • Placebo — DIETARY_SUPPLEMENT
    Oral hypromellose capsule with all inactive ingredients but lacking the Magnolia officinalis bark extract

Study Details

The goal of this clinical trial is to evaluate whether Viv, a consumer-grade dietary supplement derived from the Magnolia officinalis plant, has an effect on biomarkers of immune activity in adults with psoriasis. To address this question, this trial will compare Viv to a placebo (a look-alike substance that contains no drug). Participants will: * Take Viv or a placebo every day for 3 months. * Complete electronic questionnaires about their quality of life and psoriasis symptoms at the beginning of the study and again at 1 months and 3 months. * Be provided with at home blood collection kits, which they will use to collect blood at the beginning of the study and again at 1 months and 3 months. Researchers will analyze these blood samples to measure the levels of specific inflammatory proteins and evaluate how they change over the course of the study in the participants taking Viv compared to those taking placebo.

Key Dates

Start date
Mar 1, 2026
Status verified
Mar 2026
Primary completion
Sep 1, 2028
Completion
Sep 1, 2029

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Viv
    Magnolia officinalis study arm
  • Placebo Comparator: Placebo
    Placebo control study arm

Primary Outcome Measure

Relative change in plasma Beta defensin 2 from baseline [ Time Frame: From baseline to the end of study product/placebo use at 12 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Decentralized Study Coordinating CenterEnglewoodNew Jersey07631
Viv Clinical Trial Operations

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