The Impact of Anesthetics on FLIP

Conditions

FLIP Imaging under various standard of care anesthetics in the context of endotracheal intubation. — DIAGNOSTIC_TEST
FLIP imaging will occur twice per subject with the same baseline (propofol) assessment and then a second study assessment with propofol, sevofluorane, or isofluorane.

To understand the impact of commonly used anesthetics on esophageal motility during FLIP topography.

Placebo Comparator: propofol-propofol
This is the control comparison of a subject undergoing FLIP imaging under the baseline scenario of propofol alone and then the again for a second time under propofol alone.
Active Comparator: propofol-SEVO
This is the the study comparison group of a subject undergoing FLIP imaging under the baseline scenario of propofol alone and then the again for a second time but this time under the anesthetic gas sevofluorane.
Active Comparator: propofol-ISO
This is the the study comparison group of a subject undergoing FLIP imaging under the baseline scenario of propofol alone and then the again for a second time but this time under the anesthetic gas isofluorane.

Distensibility [ Time Frame: at 10 min ]

Facility	City	State	ZIP	Site coordinators
Baylor University Medical Center - Jonsson Building	Dallas	Texas	75246	-

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