Clinical Study to Assess the Efficacy of New Toothpaste Containing SnF as Compared to Colgate Cavity Protection Toothpaste on the Reduction of Enamel Erosion

Part of paid clinical trials in San Antonio, Texas.

Sponsor
Colgate Palmolive
Study ID
NCT07442136
Phase
PHASE3
Status
Active Not Recruiting

Conditions

  • Enamel Erosion

Eligibility Criteria

Sex
ALL
Age
18 Years - 70 Years
Healthy Volunteers
Accepted

Interventions

  • New Toothpaste Containing SnF — DRUG
    Participants will brush with a new toothpaste containing SnF for two minutes twice daily.
  • Fluoride Toothpaste — DRUG
    Participants will brush with a regular fluoride toothpaste twice daily for two minutes.

Study Details

The goal of this clinical trial is to learn if a new toothpaste can prevent enamel erosion in healthy adults. Researchers will compare the test toothpaste to a control toothpaste to see if there is a difference in erosion levels. Participants will brush twice a day for two minutes with their assigned toothpaste.

Key Dates

Start date
Mar 3, 2026
Status verified
May 2026
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
80 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Test
    Participants will brush with a new toothpaste Containing SnF for two minutes twice daily.
  • Placebo Comparator: Control
    Participants will brush with a regular fluoride toothpaste for two minutes twice daily.

Primary Outcome Measure

Surface loss [ Time Frame: From baseline to the end of treatment at 10 days. ]

Locations (1)

FacilityCityStateZIPSite coordinators
School of Dentistry, University of Texas Health San AntonioSan AntonioTexas78229-

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