Sarcopenia in Chronic Kidney Disease (CKD) Patients

Part of paid clinical trials in San Antonio, Texas.

Sponsor
The University of Texas Health Science Center at San Antonio
Study ID
NCT07437053
Phase
EARLY_PHASE1
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
45 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Valine — DRUG
    A medical food intended for use under medical supervision
  • EEA — DRUG
    A medical food intended for use under medical supervision

Study Details

Sarcopenia, or loss of muscle and strength is common in patients with poor kidney function. Although a high protein diet is generally recommended for sarcopenia, patients with poor kidney function are advised to follow a low-protein diet. In this study, we will evaluate the practicality and potential benefits of two different amino acids (molecules that form proteins) in improving sarcopenia in patients with advanced kidney disease. The study aims to improve muscle mass and strength. All study procedures are free of cost and do not require significant time commitment. You will have time to ask questions and discuss the study with your family, primary care physician, and your kidney doctor to make the decision if this is right study for you to participate in.

Key Dates

Start date
Jun 1, 2026
Status verified
Feb 2026
Primary completion
Jul 31, 2027
Completion
Oct 30, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment group Valine
    Daily oral consumption of 2 g valine, divided into two meals (1 g per meal, one packet), each equivalent to approximately 0.8 g of protein.
  • Experimental: Treatment group EEA
    Daily oral consumption of 20 g essential amino acids (EAA), divided into two meals (10 g per meal, one packet), each equivalent to 5 g of protein and 3.14 g of branched chain amino acids (BCAA).

Primary Outcome Measure

Skeletal muscle strength (handgrip strength test) [ Time Frame: Baseline to 14 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The University of Texas Health Science Center at San AntonioSan AntonioTexas78229
Subrata Debnath, PhD
[email protected]
210-567-4700

Find similar trials in San Antonio, TX

By condition
Chronic kidney disease
By specialty
NephrologyKidney disease
By research site
The University of Texas Health Science Center at San Antonio· San Antonio, TX

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