A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis

Part of paid clinical trials in Aurora, Colorado.

Sponsor
Bristol-Myers Squibb
Study ID
NCT07412704
Phase
PHASE1/PHASE2
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • BMS-986528 — DRUG
    Specified dose on specified days

Study Details

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and the preliminary evidence of disease-modifying effect of BMS-986528 in participants with refractory, difficult-to-treat rheumatoid arthritis (RA).

Key Dates

Start date
May 28, 2026
Status verified
Feb 2026
Primary completion
Oct 30, 2029
Completion
Sep 2, 2030

Study Design

Enrollment
84 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Cohort A1
  • Experimental: Cohort A2
  • Experimental: Cohort A3
  • Experimental: Cohort A4
  • Experimental: Cohort A5
  • Experimental: Cohort A6
  • Experimental: Cohort A7
  • Experimental: Cohort A8
  • Experimental: Cohort B1
  • Experimental: Cohort B2

Primary Outcome Measure

Number of participants with treatment-emergent adverse events (TEAEs) [ Time Frame: Up to Week 54 ]

Central Contacts

  • BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
    855-907-3286
    [email protected]
  • First line of the email MUST contain NCT # and Site #.

Locations (5)

FacilityCityStateZIPSite coordinators
Local Institution - 0050AuroraColorado80045
Site 0050
Local Institution - 0055South MiamiFlorida33143
Site 0055
Local Institution - 0066PortlandOregon97239
Site 0066
Local Institution - 0051DeSotoTexas75115-
Local Institution - 0057San AntonioTexas78229
Site 0057

Find similar trials in Aurora, CO

By condition
Rheumatoid arthritis
By specialty
RheumatologyAutoimmune diseaseMusculoskeletal disorders
By research site
Local Institution - 0050· Aurora, COLocal Institution - 0055· South Miami, FLLocal Institution - 0066· Portland, ORLocal Institution - 0051· DeSoto, TXLocal Institution - 0057· San Antonio, TX

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