Stimulation of External Carotid Artery Circulation

Part of paid clinical trials in Galveston, Texas.

Sponsor
The University of Texas Medical Branch, Galveston
Study ID
NCT07402954
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • Cadwell Cascade 32 PRO — DEVICE
    Cascade 32 PRO will be to gently deliver electrical pulses.

Study Details

This study is testing a new approach to help people with migraine headaches. Researchers want to find out if using electrical stimulation to affect blood flow in the external carotid artery is safe and practical for helping control headaches. The goal of the study is to determine whether this approach could improve headache symptoms and overall outcomes for people with migraines.

Key Dates

Start date
Jan 16, 2026
Status verified
Feb 2026
Primary completion
Aug 31, 2027
Completion
Aug 31, 2027

Study Design

Enrollment
12 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Single intervention arm
    Participants will undergo the planned external carotid artery circulation procedure. Before the lidocaine infusion begins, bipolar stimulation will be delivered through the external carotid artery circulation. During stimulation, clinicians will record vital signs, neurologic status, and headache severity using a 0-10 scale. Continuous intra-procedural monitoring will also be performed. After bipolar stimulation is completed, participants will receive lidocaine infusion as planned.

Primary Outcome Measure

Safety of Bipolar external carotid artery circulation Stimulation [ Time Frame: Measured Perioperative/Periprocedural and through the immediate post-procedural period (up to 24 hours). ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Texas Medical BranchGalvestonTexas77555-0133
Matias Costa, MD
[email protected]

Find similar trials in Galveston, TX

By condition
Migraine
By specialty
Neurology
By research site
University of Texas Medical Branch· Galveston, TX

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