A Clinical Study in Healthy Adults to See How the Body Processes and How Safe a Tablet That Combines Gemigliptin, Dapagliflozin, and Metformin is, Compared With Taking Zemiglo and Xigduo XR Together While Fasting.
- Sponsor
- LG Chem
- Study ID
- NCT07399470
- Phase
- PHASE1
- Status
- Active Not Recruiting
Conditions
- Fasting Conditions
- Healthy Volunteers
Eligibility Criteria
- Sex
- ALL
- Age
- 19 Years - 50 Years
- Healthy Volunteers
- Accepted
Interventions
- Test drug: Fixed-dose combination of gemigliptin/dapagliflozin/metformin 50/10/1000 mg — DRUGAll participants will take 1 tablet of either test drug or 2 tablets of reference drug with fasting conditions.
- Reference drug: Gemigliptin (Zemiglo) 50mg, Dapagliflozin/metformin (Xigduo XR) 10/1000 mg — DRUGAll participants will take 1 tablet of either test drug or 2 tablest of reference drug with fasting conditions.
Study Details
Bioequivalence study for the fixed-dose combination of Gemigliptin/Dapagliflozin/Metformin 50/10/1000 mg under fasting conditions in healthy volunteers
Key Dates
- Start date
- Jan 9, 2026
- Status verified
- Feb 2026
- Primary completion
- Feb 28, 2026
- Completion
- Feb 28, 2026
Study Design
- Enrollment
- 58 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- CROSSOVER
- Primary purpose
- OTHER
Arms
- Experimental: Sequence 1test drug \> reference drug
- Experimental: Sequence 2reference drug \> test drug
Primary Outcome Measure
The plasma concentration of Gemigliptin, Dapagliflozin and Metformin [ Time Frame: Up to 72 hours ]
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