Sex Differences in E-Cigarette Perception

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Yale University
Study ID
NCT07398976
Status
Not Yet Recruiting

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Conditions

  • E-cigarette Use
  • Nicotine Dependence

Eligibility Criteria

Sex
ALL
Age
21 Years - 44 Years
Healthy Volunteers
Accepted

Interventions

  • Nicotine Level 1 (0mg/ml) — OTHER
    Menthol with be paired with 0mg/ml nicotine in an e-cigarette
  • Nicotine Level 2 (36mg/ml) — OTHER
    Menthol with be paired with 36mg/ml nicotine in an e-cigarette
  • Nicotine Level 3 (59mg/ml) — OTHER
    Menthol with be paired with 59mg/ml nicotine in an e-cigarette

Study Details

This study examines differences between males and females in the appeal and addiction potential of menthol flavored e-cigarettes with and without nicotine.

Key Dates

Start date
Jun 15, 2026
Status verified
May 2026
Primary completion
Apr 1, 2027
Completion
Apr 1, 2027

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER

Arms

  • Experimental: Sampling Session - Lab 1
    Participants will sample and rate three menthol flavored e-cigarettes with varying levels of nicotine.
  • Experimental: Concurrent Choice Session- Lab 2
    Participants will make choices between two menthol e-cigarettes with different levels of nicotine.

Primary Outcome Measure

Proportion of Choices [ Time Frame: For the 3 hour period of the Lab 2 preference task ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Yale School of MedicineNew HavenConnecticut06473
Danielle R Davis, PhD
203-974-7607

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