Cognition and Behavior With Sham Accelerated TMS

Part of paid clinical trials in Sacramento, California.

Sponsor
University of California, Davis
Study ID
NCT07397858
Status
Recruiting
Apply to this trial

Conditions

  • Healthy Participants

Eligibility Criteria

Sex
ALL
Age
15 Years - 25 Years
Healthy Volunteers
Accepted

Interventions

  • Transcranial Magnetic Stimulation Sham — DEVICE
    All study participants will receive sham TMS (no active stimulation will be provided).

Study Details

The goal of this clinical study is to understand how a person's expectations about treatment can influence their mood, motivation, and reactions to everyday rewards. The study includes young people ages 15-25 who will complete a sham (placebo) version of an accelerated transcranial magnetic stimulation (TMS) treatment. No active brain stimulation is given. The main questions this study aims to answer are: 1. Do expectancy and treatment beliefs change during and after an accelerated sham TMS schedule? 2. Do these expectations influence mood, reward processing, or craving? 3. Does a more intensive schedule of sham sessions lead to different expectancy effects than a slower, once-daily schedule? Participants will: * Complete baseline clinical assessments and an MRI session * Undergo five days of accelerated sham TMS (no active brain stimulation is delivered) * Complete post-treatment MRI and follow-up assessments at 1 week and 4 weeks

Key Dates

Start date
Apr 11, 2026
Status verified
Apr 2026
Primary completion
Aug 31, 2027
Completion
Jan 31, 2028

Study Design

Enrollment
25 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Other: Open label sham
    All study participants will receive sham TMS (no active stimulation will be provided).

Primary Outcome Measure

Accelerated sham TMS feasibility [ Time Frame: From enrollment to end of study at 5 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
UC Davis Medical CenterSacramentoCalifornia95817
Manpreet Kaur Singh, MD, MS
[email protected]
650-862-5654
Maitri Khanna, BS
[email protected]
6996662054

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By research site
UC Davis Medical Center· Sacramento, CA

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