Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT07397117
Status
Recruiting
Apply to this trial

Conditions

  • Sciatica Acute

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • nerve block with ropivacaine — PROCEDURE
    Ultrasound-guided transgluteal sciatic nerve block with 10-20 mL of 0.2% ropivacaine injected around the affected sciatic nerve at the level of the greater trochanter
  • Standard medical treatment — OTHER
    Standard ED analgesic management per departmental protocols (oral/IV NSAIDs, acetaminophen, opioids, muscle relaxants).

Study Details

The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department. The main question it aims to answer is: Is a transgluteal sciatic nerve block better than standard of care in improving pain in ER patients with sciatic back pain? If there is a comparison group: Researchers will compare patients who receive transgluteal sciatic nerve blocks to patients who receive standard of care to see if pain scores improve in ER patients with sciatic back pain. Participants will be randomized into the transgluteal sciatic nerve block group or the control group (standard of care). Participants will be asked to answer questions about their pain and will be asked to walk a timed short distance.

Key Dates

Start date
May 26, 2026
Status verified
May 2026
Primary completion
Dec 31, 2026
Completion
Jan 31, 2027

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Transgluteal sciatic nerve block
    Patients will receive an ultrasound-guided transgluteal sciatic nerve block with 10-20 mL of 0.2% ropivacaine injected around the affected sciatic nerve at the level of the greater trochanter.
  • Active Comparator: Standard of care
    Standard ED analgesic management per departmental protocols (oral/IV NSAIDs, acetaminophen, opioids, muscle relaxants).

Primary Outcome Measure

Pain scores [ Time Frame: 30 minutes after intervention, time of ED disposition (at decision point of admission to the hospital or discharge which can be up to 6 hours), 24 hours after ED visit, 48 hours after ED visit ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, San FranciscoSan FranciscoCalifornia94107
Tianyu Tang, MD
[email protected]
628-247-7578
Kavita Gandhi, MD (SUB_INVESTIGATOR)
Nancy Anaya, MD (SUB_INVESTIGATOR)
Jeffrey Merz-Herrala, MD (SUB_INVESTIGATOR)
Tianyu Tang, MD (SUB_INVESTIGATOR)
Felipe Ocampo, MD (SUB_INVESTIGATOR)
Jeanne Noble, MD (PRINCIPAL_INVESTIGATOR)

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By research site
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