UCSF Center for Genome Surgery Biobank and Registry

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT07396285
Status
Not Yet Recruiting

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Conditions

  • Any Conditions That Are Genetic or Suspected to be Genetic in Origin

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Accepted

Study Details

Gene editing approaches (including but not limited to: CRISPR, LNP, AAV, RNAi etc.) for the medical specialty of interventional genomics require (1) determination of the clinical relevance of genomic variants and (2) systematic evaluation of the 'editability' of those variants. Here, we seek to use in silico and in vitro analyses of genomic, cellular, and clinical data/specimens to (1) identify novel pathogenic variants underlying diseases and (2) examine the specificity and efficacy of various gene editing components across the entire human genomic landscape.

Key Dates

Start date
May 1, 2026
Status verified
Feb 2026
Primary completion
Dec 31, 2050
Completion
Dec 31, 2050

Study Design

Enrollment
10,000 participants (estimated)

Arms

  • Arm: Center for Genome Surgery Case Series Discussion
  • Arm: Enrollment in Registry and Biobank

Primary Outcome Measure

Improve our understanding of how specific mutations lead to dysfunction and cause disease [ Time Frame: Up to 25 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, San FranciscoSan FranciscoCalifornia94143-

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