Ankylosing Spondylitis

Sponsor
Sohag University
Study ID
NCT07396194
Status
Not Yet Recruiting

Notify me when recruiting opens

Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.

Not yet recruiting

Add your contact details and location so we can keep your interest tied to this study.

Conditions

Eligibility Criteria

Sex
ALL
Age
16 Years - 80 Years
Healthy Volunteers
Accepted

Study Details

The goal of this observational study is to measure the serum level of cytokines IL-17, IL-38,IL-41, and gene expression of HLA-B27 gene in ankylosing spondylitis patients and healthy control group. The main question it aims to answer is: Does the disease activity, severity, serum level of cytokines (IL-17, IL-38, and IL-41) are affected by the HLA-b27 gene positivity? Researchers will compare the serum level of cytokines IL-17, IL-38,IL-41, and gene expression of HLA-B27 gene in ankylosing spondylitis patients and healthy control group to see if there significant differences in serum levels of interleukins 17, 38, 41 in AS patients and healthy control group. .

Key Dates

Start date
Mar 1, 2026
Status verified
Jan 2026
Primary completion
Dec 30, 2026
Completion
Mar 1, 2027

Study Design

Enrollment
84 participants (estimated)

Arms

  • Arm: Cases
    Patients with Ankylosing spondylitis
  • Arm: Healthy Controls
    Participants Without Ankylosing spondylitis

Primary Outcome Measure

collection of blood samples from paticipants [ Time Frame: from March 2026 to August 2026 ]

Central Contacts

Related Studies