Electrophysiological Representations of Odor Identity Study 2

Conditions

• Odor Identity Ratings

Eligibility Criteria

Sex

ALL

Age

12 Years - 65 Years

Healthy Volunteers

Not accepted

Interventions

• odor — BEHAVIORAL
  present odor

Study Details

To identify a neural representation of odor identity, it is necessary to dissociate molecular structure from perceptual identity/similarity. Whether the olfactory system employs a coding scheme in which the similarity between neural features is systematically related to perceptual similarity is unknown. Experiments for this aim will acquire perceptual responses while manipulating perceptual similarity. In Experiment 1A, we will examine features of neural responses during natural behavior of freely naming odors. In Experiment 1B, we will manipulate perceptual similarity with odor metamers and collect perceptual and neural data on each trial. Preliminary data suggest that the earliest, high-frequency components of the piriform response can optimally decode perceptual identity.

Key Dates

Start date

Mar 5, 2025

Status verified

Jan 2026

Primary completion

Mar 1, 2028

Completion

Oct 1, 2028

Study Design

Enrollment

28 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Arms

• Experimental: Investigating representations of odor identity in human piriform cortex.
  Odors will be presented and identified

Primary Outcome Measure

Perceived odor identity [ Time Frame: 15 minutes ]

Central Contacts

• Naelly Arriaga, MPH
  312-503-7244
  [email protected]

Locations (1)

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