Zesty Exercise System for Therapeutic Engagement

Part of paid clinical trials in Atlanta, Georgia.

Sponsor
Emory University
Study ID
NCT07382674
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • ZEST-E Robot-Assisted Exercise Program — DEVICE
    Participants complete robot-guided exercises using the ZEST-E system. Sessions include reaching, stretching, and dual-task movements for upper and lower limbs. Before each exercise, participants view a video demonstration or receive instruction from staff. ZEST-E presents targets to tap with hands, feet, or knees and uses calibration and practice trials to set positions. The robot operates with force-limited controls, back-drivable joints, and an emergency run-stop button. Participants may request to stop the robot at any time. All participants begin with seated exercises in week 1 and may progress to standing exercises in weeks 2-3 after completing a safety tutorial. Safety supports such as mats, chairs, and gait belts are used during standing tasks. Training will consist of 1-hour bouts, 3 times/week for 3 weeks

Study Details

This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely. Participants will complete robot-guided exercise three times per week for three weeks. The study will assess feasibility, retention, safety, acceptability, and tolerability of remotely monitored ZEST-E and will measure changes in functional performance using the Standing Forward Reach test and the 30-Second Chair Stand test. These outcomes reflect range of motion and lower-body strength targeted by the exercise program.

Key Dates

Start date
Mar 16, 2026
Status verified
May 2026
Primary completion
Feb 29, 2028
Completion
Feb 29, 2028

Study Design

Enrollment
46 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: In-Person Monitored ZEST-E Exercise
    Participants complete ZEST-E exercise sessions with a researcher or physical therapist present in the same room to provide safety oversight. All participants begin with seated exercises in week 1 and may progress to standing exercises in weeks 2 and 3 after completing a safety tutorial and demonstrating understanding of standing-exercise precautions. The researcher monitors the robot, provides instructions, and may stop the robot at any time using the run-stop button if needed.
  • Experimental: Remotely Monitored ZEST-E Exercise
    Participants complete ZEST-E exercise sessions while the researcher or physical therapist monitors the session remotely via camera from outside the room. A trained caregiver is present in the room to provide safety oversight and to activate the robot's run-stop button if needed. Participants follow the same progression from seated to standing exercises as in the in-person arm, contingent on completion of the safety tutorial and demonstration of safe technique.

Primary Outcome Measure

Standing Forward Reach (SFR) Test [ Time Frame: Baseline, after 3 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Emory University, 57 Executive Park S NE, Ste 200AtlantaGeorgia30329
Madeleine Hackney, PhD
[email protected]

Find similar trials in Atlanta, GA

By condition
Parkinson's disease
By specialty
NeurologyBrain disorders
By research site
Emory University, 57 Executive Park S NE, Ste 200· Atlanta, GA

Related Studies