Study of DISC-0974-201 in Participants With IBD and Anemia

Part of paid clinical trials in Scottsdale, Arizona.

Sponsor
Disc Medicine, Inc
Study ID
NCT07368972
Phase
PHASE2
Status
Recruiting
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Conditions

  • Anemia
  • Inflammatory Bowel Disease (IBD)
  • Inflammatory Bowel Disease (IBD); Anemia

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • DISC-0974 — DRUG
    DISC-0974 is administered subcutaneously.
  • Placebo — DRUG
    Placebo is administered subcutaneously

Study Details

This is a Phase 2, multicenter, randomized, double-blind placebo-controlled study of DISC-0974 to evaluate safety, tolerability, and efficacy in participants with IBD and anemia of inflammation.

Key Dates

Start date
Feb 20, 2026
Status verified
Mar 2026
Primary completion
Oct 31, 2026
Completion
Mar 31, 2027

Study Design

Enrollment
21 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Active
    DISC-0974 60 mg (n = 14) administered subcutaneously (SC) every 28 days for 3 doses
  • Placebo Comparator: Placebo
    Placebo (n = 7) administered SC every 28 days for 3 doses

Primary Outcome Measure

Maximal change from baseline in Hgb through Day 85 [ Time Frame: up to 85 days ]

Central Contacts

Locations (9)

FacilityCityStateZIPSite coordinators
One of a Kind Clinical Research Center, LLCScottsdaleArizona85258
Dalena Tran
[email protected]
602-820-6906
Brittney Calivoso
[email protected]
602-820-6906
Florin Gaidici, MD (PRINCIPAL_INVESTIGATOR)
Dolphin Medical ResearchDoralFlorida33172
Alicia Lopez
[email protected]
305-510-3392
Ivette Cuevas
[email protected]
305-870-5999
Otto Marquez-Mendoza, MD (PRINCIPAL_INVESTIGATOR)
Clinical Research of Osceola, LLCKissimmeeFlorida34741
Victor Sanchez
[email protected]
407-954-4016
Basher Atiquzzaman, MD (PRINCIPAL_INVESTIGATOR)
Anchor Medical Research, LLCMiamiFlorida33176
Yoany Rodriguez
[email protected]
786-384-7005
Aslenys Garcia
[email protected]
786-384-7005
Juvenal E Martinez, MD, PA (PRINCIPAL_INVESTIGATOR)
Ezy Medical Research, CoMiami LakesFlorida33015
Priscilla Hernandez
[email protected]
786-483-8162
Katherine Torrado
[email protected]
786-483-8162
Jorge Paoli-Bruno, MD, MBA, FACHE, CPE, FAAFP (PRINCIPAL_INVESTIGATOR)
Guardian Angel Research, IncTampaFlorida33614
Gabriela Morales
[email protected]
813-512-7479
Claudia Rendon
[email protected]
813-512-7479
Mario F Hernandez, MD (PRINCIPAL_INVESTIGATOR)
KAD Clinical ResearchSt LouisMissouri63123
Kristina Wriston
[email protected]
1-314-254-3168
Michael Tarvin
[email protected]
1-314-254-3168
Adrian Di Bisceglie, M. Med (PRINCIPAL_INVESTIGATOR)
One of a Kind Clinical Research Center, LLCKingwoodTexas77339
Natalie Verduzco
[email protected]
346-847-9375
Brittney Calivoso
[email protected]
346-847-9375
Sushovan Guha, MD, MA, PhD, FASGE, AGAF (PRINCIPAL_INVESTIGATOR)
Siena Research NetworkSugar LandTexas77479
Shahin Mozaffari
[email protected]
832 691 0205
Mehjabin Parkar, MD (PRINCIPAL_INVESTIGATOR)

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One of a Kind Clinical Research Center, LLC· Scottsdale, AZDolphin Medical Research· Doral, FLClinical Research of Osceola, LLC· Kissimmee, FLAnchor Medical Research, LLC· Miami, FLEzy Medical Research, Co· Miami Lakes, FLGuardian Angel Research, Inc· Tampa, FL

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