Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer

Part of paid clinical trials in St. Petersburg, Florida.

Sponsor
Merus B.V.
Study ID
NCT07353957
Phase
PHASE2
Status
Recruiting
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Conditions

  • Lung Cancer - Non Small Cell Non-Squamous
  • Lung Cancer - Non Small Cell Squamous

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The study will test the efficacy and safety of petosemtamab in combination with Pembrolizumab in first line patients with squamous non-small cell lung cancer and non-squamous non-small cell lung cancer.

Key Dates

Start date
Mar 27, 2025
Status verified
Jan 2026
Primary completion
May 31, 2028
Completion
Feb 27, 2031

Study Design

Enrollment
180 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: First line squamous non-small cell lung cancer patients
  • Experimental: First line non-squamous non-small cell lung cancer patients

Primary Outcome Measure

Objective response rate per investigator assessment [ Time Frame: Up to 4.5 years ]

Central Contacts

Locations (6)

FacilityCityStateZIPSite coordinators
Florida Cancer Specialists - NorthSt. PetersburgFlorida33701-4553
Memorial Sloan Kettering Cancer CenterLong Island CityNew York11101
Paul Paik, MD
[email protected]
646-129-7200
Tennessee Site 2ChattanoogaTennessee37403
Study Coordinator
[email protected]
877-836-6662
Tennessee Site 1NashvilleTennessee37209
Study Coordinator
[email protected]
877-836-6662
Virginia Site 2BlacksburgVirginia24060-
Virginia Site 1FairfaxVirginia22031
Study Coordinator
[email protected]
703-636-1473

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Florida Cancer Specialists - North· St. Petersburg, FLMemorial Sloan Kettering Cancer Center· Long Island City, NYTennessee· Chattanooga, TNTennessee· Nashville, TNVirginia· Blacksburg, VAVirginia· Fairfax, VA