Cigarette Filter Study

Conditions

• Smoking ( Cigarette)

Eligibility Criteria

Sex

ALL

Age

21 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Charcoal filtered cigarettes with marketing — BEHAVIORAL
  After completing a 7-day baseline period of smoking their own preferred brand, participants randomized to the charcoal filtered cigarette with marketing condition will use Natural American Spirit Sky cigarettes for the next 28 days
• Charcoal filtered cigarette without marketing — BEHAVIORAL
  After completing a 7-day baseline period of smoking their own preferred brand, participants randomized to the charcoal filtered cigarette without marketing condition will use Tareyton cigarettes for the next 28 days
• Non-charcoal filtered cigarettes — BEHAVIORAL
  After completing a 7-day baseline period of smoking their own preferred brand, participants randomized to the non-charcoal filtered cigarette condition will use Natural American Spirit Yellow cigarettes for the next 28 days

Study Details

The overall purpose of this study is to determine the effects of using charcoal-filtered cigarettes on product perceptions, smoking behaviors, and biomarkers of exposure to tobacco-related toxicants. The main questions it aims to answer are: Do perceptions of cigarettes differ by their filter? Do people smoke charcoal-filtered cigarettes differently than cigarettes with conventional filters, and does this change their exposure to cigarette harms? Study participants will complete a 5-week laboratory-based, open-label, parallel-design randomized trial. After a baseline period of smoking their preferred brand, participants will smoke charcoal-filtered or non-charcoal-filtered cigarettes for 4 weeks while completing weekly sessions to assess primary outcomes. During weekly sessions, they will smoke two cigarettes in our laboratory, provide urine and carbon monoxide samples, and complete questionnaires.

Key Dates

Start date

Apr 27, 2026

Status verified

Jun 2026

Primary completion

Dec 31, 2030

Completion

Dec 31, 2030

Study Design

Enrollment

252 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Arms

• Experimental: NAS Sky charcoal-filtered cigarettes
  Charcoal-filtered cigarettes
• Active Comparator: NAS Yellow non-charcoal-filtered cigarettes
  Conventional-filtered cigarettes
• Experimental: Tareyton charcoal cigarettes
  Charcoal-filtered cigarettes

Primary Outcome Measure

Risk beliefs [ Time Frame: Day 35 ]

Central Contacts

• Matthew Joy, MPH
  848-267-8284
  [email protected]

Locations (1)

Find similar trials in New Brunswick, NJ

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