Blood Flow Restriction Resistance Exercise and Cardiac Cycle Dynamics

Part of paid clinical trials in Montclair, New Jersey.

Sponsor
Montclair State University
Study ID
NCT07344740
Status
Not Yet Recruiting

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Conditions

  • Cardiac

Eligibility Criteria

Sex
ALL
Age
18 Years - 50 Years
Healthy Volunteers
Accepted

Interventions

  • Blood flow restriction resistance exercise — BEHAVIORAL
    Blood flow in and out of the limb will be artificially with an occlusion cuff.

Study Details

Blood flow restriction resistance exercise uses partial vascular occlusion of a limb during low weight resistance exercises to stimulate muscle strengthening and growth. This is commonly used during rehabilitation from an injury. Because blood flow in and out of the limbs is decreased, this may have consequences for blood flow through the heart. The purpose of this study will be to test cardiac dynamics during blood flow restriction resistance exercise to determine if cardiac blood flow is impacted. It is hypothesized that both non-BFR exercise and BFR exercise will increase heart rate shortening various cardiac cycle parameters, but BFR exercise will increase the isovolumetric contraction time vs non-BFR exercise due to an increase in total peripheral resistance. It is also hypothesized that BFR exercise will lower early ventricular filling parameters due to lower venous return.

Key Dates

Start date
Feb 1, 2026
Status verified
Feb 2026
Primary completion
Jan 1, 2028
Completion
Jan 1, 2028

Study Design

Enrollment
40 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Intervention group
    Blood flow restriction resistance exercise

Primary Outcome Measure

Cardiac cycle durations [ Time Frame: During the intervention for approximately 10 minutes. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Montclair State UniversityMontclairNew Jersey07043
Francine Seruya
[email protected]
973-655-7583
Kim Blatt
[email protected]
Evan L Matthews (PRINCIPAL_INVESTIGATOR)

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By research site
Montclair State University· Montclair, NJ

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