Assessing Obesity Related Risk Factors in Adult Population: A Genetic and Behavioral Study

Part of paid clinical trials in Augusta, Georgia.

Sponsor
Augusta University
Study ID
NCT07341841
Status
Enrolling By Invitation

Conditions

  • Obesity Prevention

Eligibility Criteria

Sex
ALL
Age
18 Years - 70 Years
Healthy Volunteers
Accepted

Interventions

  • Diet and exercise — BEHAVIORAL
    Diet intervention: Participants will be randomly divided into a control group (n=50) and a training group (n=50) using the simplest method of assigning participants to different treatment groups: a coin toss. They will be surveyed using the modified DHII questionnaire to assess their caloric intake. The baseline calorie intake will be evaluated during the first visit. Participants will be instructed to reduce their portion sizes by half of what they typically consume. The commitment of participants will be for 8 weeks. Exercise intervention: In the first visit, subjects will be familiarized with exercise on a bicycle ergometer to eliminate the novel effects of a new experience. The subjects in the training group will then come to our laboratory to participate in an 8-week exercise program; the control group will not undergo training during this experimental period. The training group will train on a bicycle ergometer for 30 minutes, 3 days a week, for 8 weeks.
  • Lifestyle Intervention — BEHAVIORAL
    8-week personalized diet using a personalized low-calorie diet based on the caloric intake baseline using modified Diet History Questionnaire II (DHQ II)
  • Exercise — BEHAVIORAL
    8-week personalized physical activity- subjects will be doing 30-minute exercise three times a week using a bicycle ergometer

Study Details

This study aims to explore the association between Melanocortin-4 Receptor (MC4R) polymorphisms, eating habits, and social determinants of health in a heterogeneous adult population in Georgia, USA.

Key Dates

Start date
Jan 1, 2026
Status verified
Jan 2026
Primary completion
Dec 1, 2026
Completion
Dec 1, 2026

Study Design

Enrollment
100 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING

Arms

  • Other: Screening
    Diet and exercise baseline

Primary Outcome Measure

Diet and exercise [ Time Frame: 8 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
Augusta UniversityAugustaGeorgia30912-

Find similar trials in Augusta, GA

By research site
Augusta University· Augusta, GA

Related Studies