Preoperative Hemodialysis Timing in Patients With End-Stage Kidney Disease: The POD-ESKD Pilot Trial

Part of paid clinical trials in Stanford, California.

Sponsor
Stanford University
Study ID
NCT07339202
Status
Recruiting
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Conditions

  • End Stage Kidney Disease (ESRD)
  • Hemodialysis
  • Perioperative Management

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Same-Day Hemodialysis — PROCEDURE
    Hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure (typically in the morning prior to the procedure).
  • No Same-Day Hemodialysis — PROCEDURE
    No hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure.

Study Details

The goal of this clinical trial is to evaluate the feasibility of two different preoperative hemodialysis schedules for people with end-stage kidney disease (ESKD) who undergo surgical procedures. The main questions it aims to answer are: Is it feasible to randomize participants with ESKD undergoing nonemergent surgical procedures to same-day hemodialysis versus no same-day hemodialysis? Is it safe to randomize participants with ESKD undergoing nonemergent surgical procedures to same-day hemodialysis versus no same-day hemodialysis? Researchers will compare the two hemodialysis schedules to see if the scheduling and safety profiles are the same. Participants will: Answer questions about their health up to 4 weeks before and 4 weeks after the surgical procedure. Receive hemodialysis on the day of the surgical procedure or not, depending on the study treatment assignment.

Key Dates

Start date
May 27, 2026
Status verified
Jun 2026
Primary completion
Sep 15, 2027
Completion
Oct 15, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Same-Day Hemodialysis
    Participants will receive same-day hemodialysis, defined as a hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure (typically in the morning prior to the procedure).
  • Active Comparator: No Same-Day Hemodialysis
    Participants will not receive same-day hemodialysis, defined as a hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure.

Primary Outcome Measure

Number of hours from completion of the most recent preoperative hemodialysis session to entry into the operating room [ Time Frame: up to 1 day ]

Locations (1)

FacilityCityStateZIPSite coordinators
Stanford UniversityStanfordCalifornia94305
Satvik Sharma
[email protected]
650-736-9368

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By research site
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