Impact of Reducose® on Glycemic Response and Menopausal Symptoms in Perimenopausal Women (CALM-R)

Part of paid clinical trials in Los Angeles, California.

Sponsor
Phynova Group Ltd
Study ID
NCT07333885
Status
Recruiting

Conditions

  • Glycemic Response
  • Menopause Symptoms

Eligibility Criteria

Sex
FEMALE
Age
40 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • Reducose® (Mulberry leaf extract) — DIETARY_SUPPLEMENT
    Reducose® proprietary mulberry leaf extract, 250mg, 2/day with meals
  • Placebo — DIETARY_SUPPLEMENT
    Placebo matching capsules, Microcrystalline Cellulose

Study Details

The purpose of this double-blind, randomized, placebo-controlled trial is to. evaluate daily Reducose® (mulberry leaf extract) supplementation taken with the two largest meals for 12 weeks on improving glycemic response and perimenopausal symptoms in women aged 40-60 years. Glycemic response is measured using Dexcom Stelo continuous glucose monitors during standardized test meals, and menopausal symptoms and sleep/quality-of-life outcomes are assessed using validated surveys administered through the Chloe app in a decentralized U.S. study.

Key Dates

Start date
Dec 12, 2025
Status verified
Jan 2026
Primary completion
Jun 30, 2026
Completion
Aug 31, 2026

Study Design

Enrollment
120 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Reducose® Mulberry Leaf Extract
  • Placebo Comparator: Matching Placebo

Primary Outcome Measure

Glycemic response following test meal [ Time Frame: Baseline and end-of-study test meals (Days 10, 14, and 98). ]

Locations (1)

FacilityCityStateZIPSite coordinators
People ScienceLos AngelesCalifornia90034
Project Manager
562-673-6744

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