A Clinical Study to See How the Body Handles and How Safe a Combination Tablet of Gemigliptin, Dapagliflozin, and Metformin 50/10/1000mg is Compared to Taking Gemigliptin 50mg Separately With Dapagliflozin/Metformin 10/1000mg in Healthy Adults After a Meal
- Sponsor
- LG Chem
- Study ID
- NCT07333742
- Phase
- PHASE1
- Status
- Completed
Conditions
- Fed Conditions
- Healthy Volunteer
Eligibility Criteria
- Sex
- ALL
- Age
- 19 Years - 50 Years
- Healthy Volunteers
- Accepted
Interventions
- Test drug: Fixed-dose combination (FDC) of gemigliptin/dapagliflozin/metformin 50/10/1000 mg — DRUGAll participants take 1 tablet of either test drug or reference drug after meal.
- Reference drug: gemigliptin (Zemiglo) 50mg, Xigduo XR 10/1000 mg — DRUGAll participants take 1 tablet of either test drug or reference drug after meal.
Study Details
Bioequivalence study for the fixed-dose combination of gemigliptin/dapagliflozin/metformin 50/10/1000 mg under fed conditions in healthy volunteers
Key Dates
- Start date
- Sep 29, 2025
- Status verified
- Dec 2025
- Primary completion
- Nov 27, 2025
- Completion
- Nov 27, 2025
Study Design
- Enrollment
- 50 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- CROSSOVER
- Primary purpose
- OTHER
Arms
- Experimental: Sequence ASequence A: Test drug -\> Reference drug
- Experimental: Sequence BSequence B: Reference drug -\> Test drug
Primary Outcome Measure
The plasma concentration of gemigliptin, dapagliflozin, and metformin [ Time Frame: - Period 1: 16 times up to 72 hours from IP administration - Period 2: 16 times up to 72 hours from IP administration ]
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