Nighttime Synchrony of Your Nutrition and Circadian Health

Part of paid clinical trials in Salt Lake City, Utah.

Sponsor
University of Utah
Study ID
NCT07329283
Status
Recruiting
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Conditions

  • Circadian Dysregulation
  • Circadian Misalignment
  • Circadian Rhythm
  • Insufficient Sleep
  • Lifestyle Factors
  • Light Exposure
  • Metabolism Changes
  • Sleep
  • Sleep Deprivation
  • Sleep Hygiene
  • Sleep Hygiene, Inadequate

Eligibility Criteria

Sex
ALL
Age
18 Years - 35 Years
Healthy Volunteers
Accepted

Interventions

  • Central Clock Misalignment — BEHAVIORAL
    Light exposure will be dimmed during the first 4 hours of scheduled wakefulness, with bright light exposure during the nighttime hours of extended wakefulness.
  • Peripheral Misalignment — BEHAVIORAL
    Most daily calories will be given later in the day to shift eating patterns toward the nighttime hours.

Study Details

Sleep is an important factor for overall health. This study will see how different light exposure patterns and food intake impact a person's metabolism (how the body breaks down food) when sleeping is reduced. Participants will attend 6 to 8 in-person visits to the study clinic, including three overnight stays. People will complete surveys and medical tests. The study will last about 4 to 6 months.

Key Dates

Start date
Dec 19, 2025
Status verified
Jan 2026
Primary completion
May 31, 2030
Completion
May 31, 2031

Study Design

Enrollment
120 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • No Intervention: Sleep Restriction with Central and Peripheral Alignment
    (Arm "A")-Control condition with central and peripheral aligned circadian rhythms
  • Experimental: Sleep Restriction with Central Clock Misalignment
    (Arm "B")-Misalignment of the central clock by nighttime electrical light exposure and dim-light in morning hours.
  • Experimental: Sleep Restriction with Peripheral Misalignment
    (Arm "C")-Misalignment of peripheral oscillators by shifting the majority of food intake to the nighttime hours.

Primary Outcome Measure

Insulin Sensitivity [ Time Frame: Immediately following the 5-day sleep restriction segment ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
College of Health Research Complex - University of Utah, Salt Lake City 84112Salt Lake CityUtah84112
Christopher Depner, PhD
[email protected]
8015812275
Christopher Depner, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
College of Health Research Complex - University of Utah, Salt Lake City 84112· Salt Lake City, UT

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